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Peptide record

TPDB42859

Anticancer Antifungal Antiparasitic standard
68 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB42859
Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
Peptipedia AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP
standard
No
A 68-aa standard natural multi-activity (Anticancer, Antifungal, and Antiparasitic) peptide sequence curated from Peptipedia, AFP-GFuse, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RQRDPQQQYEQCQKHCQRRETEPRHMQTCQQRCERRYEKEKRKQQKRYEEQQREDEEKYEERMKEEDN
Physicochemical Analysis
C363H584N130O126S6
AGILFSWV
E
8977.79
7.84
21
18
6
+1
57.10
-2.929
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
6210
69.17
25
Residue Composition
number
0
A
12
R
1
N
3
D
4
C
15
E
14
Q
0
G
2
H
0
I
0
L
7
K
2
M
0
F
2
P
0
S
2
T
0
W
4
Y
0
V
Amino Acid Distribution
A: 0 R: 12 N: 1 D: 3 C: 4 E: 15 Q: 14 G: 0 H: 2 I: 0 L: 0 K: 7 M: 2 F: 0 P: 2 S: 0 T: 2 W: 0 Y: 4 V: 0
Chemical Descriptors
68
C363H584N130O126S6
8977.79
7.84
+1
57.10
-2.929
Evidence Records 24 records
Evidence 1 Activity

Activity

IC50
Antifungal
5-10 µg/mL

Target

A. helianthi

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
DRAMP antifungal activity supported by activity records against fungal target organisms. dbAMP classified under the Anti-fungal function class.
Active against A. helianthi (IC50 5-10 ug/ml), C. paradoxa (IC50 20-50 ug/ml), C. nicotianae (IC50 5-10 ug/ml), C. elegans (IC50 2-5 ug
Evidence 2 Activity

Activity

IC50
Antifungal
20-50 µg/mL

Target

C. paradoxa

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against A. helianthi (IC50 5-10 ug/ml), C. paradoxa (IC50 20-50 ug/ml), C. nicotianae (IC50 5-10 ug/ml), C. elegans (IC50 2-5 ug/ml), F. oxysporum (IC50 10 ug/m
Evidence 3 Activity

Activity

IC50
Antifungal
5-10 µg/mL

Target

C. nicotianae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against A. helianthi (IC50 5-10 ug/ml), C. paradoxa (IC50 20-50 ug/ml), C. nicotianae (IC50 5-10 ug/ml), C. elegans (IC50 2-5 ug/ml), F. oxysporum (IC50 10 ug/ml), L. maculans (IC50 25 ug/ml),
Evidence 4 Activity

Activity

IC50
Antifungal
2-5 µg/mL

Target

C. elegans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

anthi (IC50 5-10 ug/ml), C. paradoxa (IC50 20-50 ug/ml), C. nicotianae (IC50 5-10 ug/ml), C. elegans (IC50 2-5 ug/ml), F. oxysporum (IC50 10 ug/ml), L. maculans (IC50 25 ug/ml), S. sclerotiorum (IC50 20-50 u
Evidence 5 Activity

Activity

IC50
Antifungal
10 µg/mL

Target

F. oxysporum

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

aradoxa (IC50 20-50 ug/ml), C. nicotianae (IC50 5-10 ug/ml), C. elegans (IC50 2-5 ug/ml), F. oxysporum (IC50 10 ug/ml), L. maculans (IC50 25 ug/ml), S. sclerotiorum (IC50 20-50 ug/ml), V. dahliae (IC50 5-10 u
Evidence 6 Activity

Activity

IC50
Antifungal
25 µg/mL

Target

L. maculans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

nicotianae (IC50 5-10 ug/ml), C. elegans (IC50 2-5 ug/ml), F. oxysporum (IC50 10 ug/ml), L. maculans (IC50 25 ug/ml), S. sclerotiorum (IC50 20-50 ug/ml), V. dahliae (IC50 5-10 ug/ml), S. cerevisiae (IC50 20
Evidence 7 Activity

Activity

IC50
Antifungal
20-50 µg/mL

Target

S. sclerotiorum

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

, C. elegans (IC50 2-5 ug/ml), F. oxysporum (IC50 10 ug/ml), L. maculans (IC50 25 ug/ml), S. sclerotiorum (IC50 20-50 ug/ml), V. dahliae (IC50 5-10 ug/ml), S. cerevisiae (IC50 20-50 ug/ml), P. cryptogea (IC50 5-10
Evidence 8 Activity

Activity

IC50
Antifungal
5-10 µg/mL

Target

V. dahliae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ysporum (IC50 10 ug/ml), L. maculans (IC50 25 ug/ml), S. sclerotiorum (IC50 20-50 ug/ml), V. dahliae (IC50 5-10 ug/ml), S. cerevisiae (IC50 20-50 ug/ml), P. cryptogea (IC50 5-10 ug/ml), P. parasitica nicotian
Evidence 9 Activity

Activity

IC50
Antifungal
20-50 µg/mL

Target

S. cerevisiae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

culans (IC50 25 ug/ml), S. sclerotiorum (IC50 20-50 ug/ml), V. dahliae (IC50 5-10 ug/ml), S. cerevisiae (IC50 20-50 ug/ml), P. cryptogea (IC50 5-10 ug/ml), P. parasitica nicotianae (IC50 10-20 ug/ml), C. michigan
Evidence 10 Activity

Activity

IC50
Antifungal
5-10 µg/mL

Target

P. cryptogea

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

iorum (IC50 20-50 ug/ml), V. dahliae (IC50 5-10 ug/ml), S. cerevisiae (IC50 20-50 ug/ml), P. cryptogea (IC50 5-10 ug/ml), P. parasitica nicotianae (IC50 10-20 ug/ml), C. michiganensis (IC50 50 ug/ml), R-solanac
Evidence 11 Activity

Activity

IC50
Antifungal
10-20 µg/mL

Target

P. parasitica nicotianae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

liae (IC50 5-10 ug/ml), S. cerevisiae (IC50 20-50 ug/ml), P. cryptogea (IC50 5-10 ug/ml), P. parasitica nicotianae (IC50 10-20 ug/ml), C. michiganensis (IC50 50 ug/ml), R-solanacearum (IC50>50 ug/ml), and E-coli (IC50>50 ug
Evidence 12 Activity

Activity

IC50
Antifungal
50 µg/mL

Target

C. michiganensis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

0-50 ug/ml), P. cryptogea (IC50 5-10 ug/ml), P. parasitica nicotianae (IC50 10-20 ug/ml), C. michiganensis (IC50 50 ug/ml), R-solanacearum (IC50>50 ug/ml), and E-coli (IC50>50 ug/ml). Also exerted nematocidal act
Evidence 13 Activity

Activity

IC50
Antiparasitic
5-10 µg/mL

Target

A. helianthi

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against A. helianthi (IC50 5-10 ug/ml), C. paradoxa (IC50 20-50 ug/ml), C. nicotianae (IC50 5-10 ug/ml), C. elegans (IC50 2-5 ug
Evidence 14 Activity

Activity

IC50
Antiparasitic
20-50 µg/mL

Target

C. paradoxa

Source & Reference

DRAMP

Other

Active against A. helianthi (IC50 5-10 ug/ml), C. paradoxa (IC50 20-50 ug/ml), C. nicotianae (IC50 5-10 ug/ml), C. elegans (IC50 2-5 ug/ml), F. oxysporum (IC50 10 ug/m
Evidence 15 Activity

Activity

IC50
Antiparasitic
5-10 µg/mL

Target

C. nicotianae

Source & Reference

DRAMP

Other

Active against A. helianthi (IC50 5-10 ug/ml), C. paradoxa (IC50 20-50 ug/ml), C. nicotianae (IC50 5-10 ug/ml), C. elegans (IC50 2-5 ug/ml), F. oxysporum (IC50 10 ug/ml), L. maculans (IC50 25 ug/ml),
Evidence 16 Activity

Activity

IC50
Antiparasitic
2-5 µg/mL

Target

C. elegans

Source & Reference

DRAMP

Other

anthi (IC50 5-10 ug/ml), C. paradoxa (IC50 20-50 ug/ml), C. nicotianae (IC50 5-10 ug/ml), C. elegans (IC50 2-5 ug/ml), F. oxysporum (IC50 10 ug/ml), L. maculans (IC50 25 ug/ml), S. sclerotiorum (IC50 20-50 u
Evidence 17 Activity

Activity

IC50
Antiparasitic
10 µg/mL

Target

F. oxysporum

Source & Reference

DRAMP

Other

aradoxa (IC50 20-50 ug/ml), C. nicotianae (IC50 5-10 ug/ml), C. elegans (IC50 2-5 ug/ml), F. oxysporum (IC50 10 ug/ml), L. maculans (IC50 25 ug/ml), S. sclerotiorum (IC50 20-50 ug/ml), V. dahliae (IC50 5-10 u
Evidence 18 Activity

Activity

IC50
Antiparasitic
25 µg/mL

Target

L. maculans

Source & Reference

DRAMP

Other

nicotianae (IC50 5-10 ug/ml), C. elegans (IC50 2-5 ug/ml), F. oxysporum (IC50 10 ug/ml), L. maculans (IC50 25 ug/ml), S. sclerotiorum (IC50 20-50 ug/ml), V. dahliae (IC50 5-10 ug/ml), S. cerevisiae (IC50 20
Evidence 19 Activity

Activity

IC50
Antiparasitic
20-50 µg/mL

Target

S. sclerotiorum

Source & Reference

DRAMP

Other

, C. elegans (IC50 2-5 ug/ml), F. oxysporum (IC50 10 ug/ml), L. maculans (IC50 25 ug/ml), S. sclerotiorum (IC50 20-50 ug/ml), V. dahliae (IC50 5-10 ug/ml), S. cerevisiae (IC50 20-50 ug/ml), P. cryptogea (IC50 5-10
Evidence 20 Activity

Activity

IC50
Antiparasitic
5-10 µg/mL

Target

V. dahliae

Source & Reference

DRAMP

Other

ysporum (IC50 10 ug/ml), L. maculans (IC50 25 ug/ml), S. sclerotiorum (IC50 20-50 ug/ml), V. dahliae (IC50 5-10 ug/ml), S. cerevisiae (IC50 20-50 ug/ml), P. cryptogea (IC50 5-10 ug/ml), P. parasitica nicotian
Evidence 21 Activity

Activity

IC50
Antiparasitic
20-50 µg/mL

Target

S. cerevisiae

Source & Reference

DRAMP

Other

culans (IC50 25 ug/ml), S. sclerotiorum (IC50 20-50 ug/ml), V. dahliae (IC50 5-10 ug/ml), S. cerevisiae (IC50 20-50 ug/ml), P. cryptogea (IC50 5-10 ug/ml), P. parasitica nicotianae (IC50 10-20 ug/ml), C. michigan
Evidence 22 Activity

Activity

IC50
Antiparasitic
5-10 µg/mL

Target

P. cryptogea

Source & Reference

DRAMP

Other

iorum (IC50 20-50 ug/ml), V. dahliae (IC50 5-10 ug/ml), S. cerevisiae (IC50 20-50 ug/ml), P. cryptogea (IC50 5-10 ug/ml), P. parasitica nicotianae (IC50 10-20 ug/ml), C. michiganensis (IC50 50 ug/ml), R-solanac
Evidence 23 Activity

Activity

IC50
Antiparasitic
10-20 µg/mL

Target

P. parasitica nicotianae

Source & Reference

DRAMP

Other

liae (IC50 5-10 ug/ml), S. cerevisiae (IC50 20-50 ug/ml), P. cryptogea (IC50 5-10 ug/ml), P. parasitica nicotianae (IC50 10-20 ug/ml), C. michiganensis (IC50 50 ug/ml), R-solanacearum (IC50>50 ug/ml), and E-coli (IC50>50 ug
Evidence 24 Activity

Activity

IC50
Antiparasitic
50 µg/mL

Target

C. michiganensis

Source & Reference

DRAMP

Other

0-50 ug/ml), P. cryptogea (IC50 5-10 ug/ml), P. parasitica nicotianae (IC50 10-20 ug/ml), C. michiganensis (IC50 50 ug/ml), R-solanacearum (IC50>50 ug/ml), and E-coli (IC50>50 ug/ml). Also exerted nematocidal act