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Peptide record

TPDB42858

Anticancer Tumor-homing Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB42858
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 20-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
RQNSCTYSDARRWALCWSGE
Physicochemical Analysis
C100H149N33O32S2
HIKMFPV
RS
2389.60
8.28
3
2
6
+1
1.20
-1.085
29.50
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
12615
527.91
9
Residue Composition
number
2
A
3
R
1
N
1
D
2
C
1
E
1
Q
1
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
3
S
1
T
2
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 3 N: 1 D: 1 C: 2 E: 1 Q: 1 G: 1 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 3 T: 1 W: 2 Y: 1 V: 0
Chemical Descriptors
20
C100H149N33O32S2
2389.60
8.28
+1
1.20
-1.085
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing (Phage display clone)
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Selection of tumor-binding ligands in cancer patients with phage display libraries
2006
Krag DN et al. Cancer Res. 2006 Aug 1 66(15):7724-33.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
Phage display library
M13 phage/Random 20 mer (X4CX10CX4) peptide library
Additional Detail Fields 2 fields
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
M13 phage/Random 20 mer (X4CX10CX4) peptide library