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Peptide record

TPDB42854

IDP-NLCa02 Anticancer standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB42854
IDP-NLCa02
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 35-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
RQIKIWFQNRRMKWKKRQRRNDLRSSFLTLRDHVP
Physicochemical Analysis
C204H334N72O48S1
ACEGY
R
4595.41
12.63
13
2
11
+10
8.87
-1.511
64.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
239.37
8
Residue Composition
number
0
A
8
R
2
N
2
D
0
C
0
E
3
Q
0
G
1
H
2
I
3
L
4
K
1
M
2
F
1
P
2
S
1
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 8 N: 2 D: 2 C: 0 E: 0 Q: 3 G: 0 H: 1 I: 2 L: 3 K: 4 M: 1 F: 2 P: 1 S: 2 T: 1 W: 2 Y: 0 V: 1
Chemical Descriptors
35
C204H334N72O48S1
4595.41
12.63
+10
8.87
-1.511
Free
L
Linear
Free
Anticancer
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

EC50
EC50 ~ 5 µM
Anticancer
5 µM

Target

Glioblastoma
RG1
Brain

Assay & Model

AlamarBlue assay
72-96 h

Source & Reference

CancerPPD 2.0
CancerPPD2
2019
WO 2019/025432 Al

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.