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Peptide record

TPDB42801

Anticancer Tumor-homing Peptides standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB42801
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 6-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
N-terminal: H2N-e9-(ahx)-X6-r9-(Cy5-labeled d-cysteinamide)
Sequence
RLQLKL
Physicochemical Analysis
C35H67N11O8
ANDCEGHIMFPSTWYV
L
769.99
11.49
2
0
3
+2
0.70
-0.083
195.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
3
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 3 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C35H67N11O8
769.99
11.49
+2
0.70
-0.083
H2N-e9-(ahx)-X6-r9-(Cy5-labeled d-cysteinamide)
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
Lung metastassis

Source & Reference

TumorHoPe2.0
TumorHoPe2
Parallel in vivo and in vitro selection using phage display identifies protease-dependent tumor-targeting peptides
2010
Whitney M et al. J Biol Chem. 2010 Jul 16 285(29):22532-41.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
PyMTmice with spontaneous progressive mammary tumors or nude mice with MDA-MB-435 clone M4A4 ( xenograft tumors).
Phage display library
M13 phage/Met-His6-E9-X6-R9 peptide library
Cy5
Additional Detail Fields 3 fields
Cy5
PyMTmice with spontaneous progressive mammary tumors or nude mice with MDA-MB-435 clone M4A4 ( xenograft tumors).
M13 phage/Met-His6-E9-X6-R9 peptide library