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Peptide record

TPDB42798

Anticancer Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB42798
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 12-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
N-terminal: Coupling at the N terminal
Sequence
RLLDTNRPLLPY
Physicochemical Analysis
C67H111N19O18
ACEQGHIKMFSWV
L
1470.73
9.87
2
1
5
+1
1.13
-0.500
130.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
101.31
3
Residue Composition
number
0
A
2
R
1
N
1
D
0
C
0
E
0
Q
0
G
0
H
0
I
4
L
0
K
0
M
0
F
2
P
0
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 0 M: 0 F: 0 P: 2 S: 0 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
12
C67H111N19O18
1470.73
9.87
+1
1.13
-0.500
Coupling at the N terminal
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
Nasopharyngeal carcinoma

Source & Reference

TumorHoPe2.0
TumorHoPe2
A novel peptide specifically binding to nasopharyngeal carcinoma for targeted drug delivery
2004
Lee TY et al. Cancer Res. 2004 Nov 1 64(21):8002-8.
US 2005/0010036

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
NPC cell line
SCID mice 4-6 weeks old with NPC-TWO1 cells
Phage display library
M13 phage/random peptide library
Liposome containing doxorubicin, 8-Hydroxypyrene-1,3,6-Trisulfonic Acid (HPTS).
Additional Detail Fields 4 fields
Liposome containing doxorubicin, 8-Hydroxypyrene-1,3,6-Trisulfonic Acid (HPTS).
NPC cell line
SCID mice 4-6 weeks old with NPC-TWO1 cells
M13 phage/random peptide library