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Peptide record

TPDB42792

mPep1 Anticancer standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB42792
mPep1
Anticancer
Cancer-related peptides
ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF pep-lab
standard
No
A 22-aa standard natural anticancer peptide sequence curated from ACP740 _ACP240, AntiCP 2.0, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
RKAFRWAWRMLKKAAPSITCVR
Physicochemical Analysis
C122H199N39O25S2
NDEQGHY
AR
2676.29
12.42
7
0
11
+7
0.15
-0.350
66.82
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
411.02
3
Residue Composition
number
4
A
4
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
1
I
1
L
3
K
1
M
1
F
1
P
1
S
1
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 4 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 3 M: 1 F: 1 P: 1 S: 1 T: 1 W: 2 Y: 0 V: 1
Chemical Descriptors
22
C122H199N39O25S2
2676.29
12.42
+7
0.15
-0.350
Free
L
Linear
Free
Antimicrobial
Bovine lactoferrin (Lf-B)
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50=8 µM
Anticancer
8 µM

Target

Skin Cancer
HL-60
Blood

Assay & Model

MTT/MTS assay
24-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2008

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.