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Peptide record

TPDB42790

PMAP-NC Anticancer standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB42790
PMAP-NC
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 23-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
RIIDRLWLVRRPQKPKFVLVWVL
Physicochemical Analysis
C142H232N40O27
ANCEGHMSTY
RLV
2931.66
12.41
6
1
13
+5
0.52
0.261
152.17
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
375.21
1
Residue Composition
number
0
A
4
R
0
N
1
D
0
C
0
E
1
Q
0
G
0
H
2
I
4
L
2
K
0
M
1
F
2
P
0
S
0
T
2
W
0
Y
4
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 2 L: 4 K: 2 M: 0 F: 1 P: 2 S: 0 T: 0 W: 2 Y: 0 V: 4
Chemical Descriptors
23
C142H232N40O27
2931.66
12.41
+5
0.52
0.261
Free
L
Linear
Free
Antimicrobial
Synthetic Analgog of PMAP-23 Synthetic Analgog of PMAP-24
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 = 6.4 µM
Anticancer
6.4 µM

Target

Breast Cancer
MDA-MB-361
Breast

Assay & Model

MTT assay
4-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 7.1 µM
Anticancer
7.1 µM

Target

Lung Cancer
A-549
Lung

Assay & Model

MTT assay
4-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023