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Peptide record

TPDB42774

P89 Anticancer Tumor-homing Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB42774
P89
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 15-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
RFRGLISLSQVYLSP
Physicochemical Analysis
C80H130N22O21
ANDCEHKMTW
LS
1736.05
11.16
2
0
7
+2
-0.94
0.313
123.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
85.83
5
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
1
I
3
L
0
K
0
M
1
F
1
P
3
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 1 L: 3 K: 0 M: 0 F: 1 P: 1 S: 3 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
15
C80H130N22O21
1736.05
11.16
+2
-0.94
0.313
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Targeting
Breast cancer
Gal beta1 --> 3GalNAc alpha disaccharide

Source & Reference

TumorHoPe2.0
TumorHoPe2
Characterization of peptides that bind the tumor-associated Thomsen-Friedenreich antigen selected from bacteriophage display libraries
1997
Peletskaya EN et al. J Mol Biol. 1997 Jul 18 270(3):374-84.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human breast carcinoma cell line MDA-MB-435
Phage display library
f3 Bacteriophage/ 15-mer peptide library
FITC
Additional Detail Fields 3 fields
FITC
Human breast carcinoma cell line MDA-MB-435
f3 Bacteriophage/ 15-mer peptide library