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Peptide record

TPDB42732

Anticancer Tumor-homing Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB42732
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 10-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
QHWSYKCIRP
Physicochemical Analysis
C60H88N18O14S1
ANDEGLMFTV
RCQHIKPSWY
1317.53
9.77
3
0
3
+2
0.58
-1.270
39.00
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
6990
530.54
4
Residue Composition
number
0
A
1
R
0
N
0
D
1
C
0
E
1
Q
0
G
1
H
1
I
0
L
1
K
0
M
0
F
1
P
1
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 0 H: 1 I: 1 L: 0 K: 1 M: 0 F: 0 P: 1 S: 1 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
10
C60H88N18O14S1
1317.53
9.77
+2
0.58
-1.270
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
Ovarian, breast, and prostate cancer
LHRH(Receptors for luteinizing hormone-releasing hormone)

Source & Reference

TumorHoPe2.0
TumorHoPe2
Tumor-specific targeting of an anticancer drug delivery system by LHRH peptide
2005
Dharap SS et al. Proc Natl Acad Sci U S A. 2005 Sep 6 102(36):12962-7.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
The human ovarian carcinoma A2780 cell line
Mice bearing xenografts of human ovarian carcinoma.female athymic nude mice
Natural
Radiolabeled with tritium (CPT-PEG-LHRH conjugate)
Additional Detail Fields 3 fields
Radiolabeled with tritium (CPT-PEG-LHRH conjugate)
The human ovarian carcinoma A2780 cell line
Mice bearing xenografts of human ovarian carcinoma.female athymic nude mice