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Peptide record

TPDB42721

P5317-28 Anticancer standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB42721
P5317-28
Anticancer
Cancer-related peptides
AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF
standard
No
A 12-aa standard natural anticancer peptide sequence curated from AntiCP 2.0, CancerPPD 2.0, Peptipedia, and other sources, with an available 3D structural model.
Sequence
QETFSDLWKLLP
Physicochemical Analysis
C70H105N15O20
ARNCGHIMYV
L
1476.69
4.07
1
2
5
-1
0.88
-0.350
97.50
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
5500
372.45
3
Residue Composition
number
0
A
0
R
0
N
1
D
0
C
1
E
1
Q
0
G
0
H
0
I
3
L
1
K
0
M
1
F
1
P
1
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 0 E: 1 Q: 1 G: 0 H: 0 I: 0 L: 3 K: 1 M: 0 F: 1 P: 1 S: 1 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
12
C70H105N15O20
1476.69
4.07
-1
0.88
-0.350
Free
L
Linear
Free
Antitumor
E3 ubiquitin-protein ligase
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 =4.7 µM
Anticancer
4.7 µM

Target

Colon Cancer
HCT-116-p53+/+
Colon

Assay & Model

Immunoprecipitation assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2011

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 =30 µM
Anticancer
30 µM

Target

Colon Cancer
HCT-116-p53+/+
Colon

Assay & Model

Immunoprecipitation assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2011