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Peptide record

TPDB42718

Anticancer Tumor-homing Peptides standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB42718
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 14-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
C-terminal: Biotinylation
Sequence
QEFSPYMGLEFKKH
Physicochemical Analysis
C81H117N19O22S1
ARNDCITWV
EKF
1740.99
7.73
3
2
5
+0
4.16
-1.021
27.86
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
1490
85.58
3
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
2
E
1
Q
1
G
1
H
0
I
1
L
2
K
1
M
2
F
1
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 2 Q: 1 G: 1 H: 1 I: 0 L: 1 K: 2 M: 1 F: 2 P: 1 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
14
C81H117N19O22S1
1740.99
7.73
+0
4.16
-1.021
Biotinylation
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Targeting
Breast cancer
Ephrin-B1

Source & Reference

TumorHoPe2.0
TumorHoPe2
EphB receptor-binding peptides identified by phage display enable design of an antagonist with ephrin-like affinity
2005
Koolpe M et al. J Biol Chem. 2005 Apr 29 280(17):17301-11.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MCF-7 human breast cancer cells
Phage display library
M13 phage / 12-mer peptide library
Biotin
Additional Detail Fields 3 fields
Biotin
MCF-7 human breast cancer cells
M13 phage / 12-mer peptide library