TPDB

3D PDB MODEL

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TPDB ID TPDB42716

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

Peptipedia dbACP dbAMP 3.0

Sequence_Type

standard

Has_Modification No

Description A 60-aa standard natural anticancer peptide sequence curated from Peptipedia, dbACP, and dbAMP 3.0, with an available 3D structural model.

Sequence

QDRPKFCYLPADPAECNAYMPRFYYDSASNKCKEFIYGGCRGNANNFKNRAECRHTCVAS

FASTA

>TPDB42716|Anticancer|length=60
QDRPKFCYLPADPAECNAYMPRFYYDSASNKCKEFIYGGCRGNANNFKNRAECRHTCVAS

Formula C297H442N88O89S7

Absent Amino Acids W

Common Amino Acids A

Mass 6893.73

PI 8.29

Basic Residues 10

Acidic Residues 6

Hydrophobic Residues 20

Net Charge +3

Boman Index 11.30

Hydrophobicity -0.847

Aliphatic Index 29.50

Half Life

Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 7825

Absorbance 280nm 113.51

Polar Residues 22

number

7

A

5

R

6

N

3

D

6

C

3

E

1

Q

3

G

1

H

1

I

1

L

4

K

1

M

4

F

4

P

3

S

1

T

0

W

5

Y

1

V

Amino Acid Distribution

A: 7 R: 5 N: 6 D: 3 C: 6 E: 3 Q: 1 G: 3 H: 1 I: 1 L: 1 K: 4 M: 1 F: 4 P: 4 S: 3 T: 1 W: 0 Y: 5 V: 1

Length

60

Formula

C297H442N88O89S7

Mass

6893.73

PI

8.29

Net Charge

+3

Boman Index

11.30

Hydrophobicity

-0.847

Evidence 1 Activity

Source & Reference

Database Source dbAMP 3.0 dbACP

Other

Source Activity Label	Source Definition
Anticancer	dbAMP 3.0 classified as Anticancer under the disease-associated peptide function classes.