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Peptide record

TPDB42711

Sample Peptide 4 from EP3604345B1 Anticancer standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB42711
Sample Peptide 4 from EP3604345B1
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 34-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
PWWWPPVVVQQQMILLIGAARKKRTLRKNDRKKR-NH2
Physicochemical Analysis
C193H319N61O42S1
CEHFSY
RK
4198.10
12.59
10
1
14
+9
5.68
-0.871
88.82
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
16500
393.03
5
Residue Composition
number
2
A
5
R
1
N
1
D
0
C
0
E
3
Q
1
G
0
H
2
I
3
L
5
K
1
M
0
F
3
P
0
S
1
T
3
W
0
Y
3
V
Amino Acid Distribution
A: 2 R: 5 N: 1 D: 1 C: 0 E: 0 Q: 3 G: 1 H: 0 I: 2 L: 3 K: 5 M: 1 F: 0 P: 3 S: 0 T: 1 W: 3 Y: 0 V: 3
Chemical Descriptors
34
C193H319N61O42S1
4198.10
12.59
+9
5.68
-0.871
Amidation
L
Linear
Free
Anticancer
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell Viability
Cell Viability = 102.6% at 25 µM
Anticancer

Target

Lung Cancer
HCC-827
Lung

Assay & Model

CCK-8 / WST-8
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023
EP3604345B1

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.