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Peptide record

TPDB42708

PS14 Anticancer standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB42708
PS14
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 14-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
PTECQVGTTCKVES
Physicochemical Analysis
C59H100N16O24S2
ARNDHILMFWY
T
1481.66
4.26
1
2
2
-1
6.28
-0.421
41.43
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
125
8.44
7
Residue Composition
number
0
A
0
R
0
N
0
D
2
C
2
E
1
Q
1
G
0
H
0
I
0
L
1
K
0
M
0
F
1
P
1
S
3
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 2 E: 2 Q: 1 G: 1 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 1 S: 1 T: 3 W: 0 Y: 0 V: 2
Chemical Descriptors
14
C59H100N16O24S2
1481.66
4.26
-1
6.28
-0.421
Free
L
Linear
Free
Anticancer and Anti-inflammatory
Aphanomyces invadans
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 = 21 µM
Anticancer
21 µM

Target

Larynx Cancer
Hep-2
Larynx

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

45.56 ± 2% LDH release at 20 µM
Anticancer

Target

Larynx Cancer
Hep-2
Larynx

Assay & Model

LDH leakage assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022