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Peptide record

TPDB42704

PS9 Anticancer standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB42704
PS9
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 9-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
PSRKVMLWS
Physicochemical Analysis
C50H82N14O12S1
ANDCEQGHIFTY
S
1103.35
11.49
2
0
4
+2
-0.06
-0.289
75.56
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
5500
498.48
2
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
1
K
1
M
0
F
1
P
2
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 1 M: 1 F: 0 P: 1 S: 2 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
9
C50H82N14O12S1
1103.35
11.49
+2
-0.06
-0.289
Free
L
Linear
Free
Anticancer
Aphanomyces invadans
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50 value range between 25.27 - 43.28 µM
Anticancer

Target

Breast Cancer
MCF-7
Breast

Assay & Model

Neutral Red Uptake assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

71.25 ± 1.3% LDH release at 40 µM
Anticancer

Target

Breast Cancer
MCF-7
Breast

Assay & Model

LDH leakage assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023