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Peptide record

TPDB42701

Anticancer Tumor-homing Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB42701
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 15-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
N-terminal: Biotinylation
Sequence
PRPGAPLAGSWPGTS
Physicochemical Analysis
C65H99N19O19
NDCEQHIKMFYV
P
1450.62
11.05
1
0
4
+1
0.29
-0.527
39.33
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
5500
379.15
3
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
1
L
0
K
0
M
0
F
4
P
2
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 4 S: 2 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
15
C65H99N19O19
1450.62
11.05
+1
0.29
-0.527
PRP
Biotinylation
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Angiogenic endothelial cell
Homing
Melanoma, Pancreatic, Brain cancer
VEGF

Source & Reference

TumorHoPe2.0
TumorHoPe2
Anti-neovascular therapy using novel peptides homing to angiogenic vessels
2002
Oku N et al. Oncogene. 2002 Apr 18 21(17):2662-9.
EP1122262A4

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human tumor tissues of islet cells of pancreas, glioblastoma of brain.
5-week-old C57BL/6 male bearing B16BL6 melanoma cells
Phage display library
M13 phage/15 mer peptide library
Radionuclide PRP-Lip -Andramycin drug
PRP-containing peptides have affinity to some molecule(s) on human angiogenic endothelial cells
Additional Detail Fields 4 fields
Radionuclide PRP-Lip -Andramycin drug
Human tumor tissues of islet cells of pancreas, glioblastoma of brain.
5-week-old C57BL/6 male bearing B16BL6 melanoma cells
M13 phage/15 mer peptide library