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Peptide record

TPDB42697

MIP(L10A) Anticancer standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB42697
MIP(L10A)
Anticancer
Cancer-related peptides
ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF pep-lab
standard
No
A 12-aa standard natural anticancer peptide sequence curated from ACP740 _ACP240, AntiCP 2.0, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
PRFWEYWLRAME
Physicochemical Analysis
C81H110N20O18S1
NDCQGHIKSTV
REW
1683.95
7.05
2
2
7
+0
-0.62
-0.867
40.83
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
12490
741.71
1
Residue Composition
number
1
A
2
R
0
N
0
D
0
C
2
E
0
Q
0
G
0
H
0
I
1
L
0
K
1
M
1
F
1
P
0
S
0
T
2
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 0 E: 2 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 1 F: 1 P: 1 S: 0 T: 0 W: 2 Y: 1 V: 0
Chemical Descriptors
12
C81H110N20O18S1
1683.95
7.05
+0
-0.62
-0.867
Free
L
Linear
Free
Antitumor
E3 ubiquitin-protein ligase
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 =1.14 µM
Anticancer
1.14 µM

Target

Colon Cancer
HCT-116-p53+/+
Colon

Assay & Model

Immunoprecipitation assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2011

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.