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Peptide record

TPDB42677

D2 Anticancer Tumor-homing Peptides standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB42677
D2
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 7-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
PNPNNST
Physicochemical Analysis
C29H46N10O13
ARDCEQGHILKMFWYV
N
742.74
6.02
0
0
0
-0
2.43
-2.171
0.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
5
Residue Composition
number
0
A
0
R
3
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
2
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 3 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 2 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
7
C29H46N10O13
742.74
6.02
-0
2.43
-2.171
PXNXXN
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor vessel
Homing
Esophagus and gastroesophageal cancer
EGFR, EGFRvIII

Source & Reference

TumorHoPe2.0
TumorHoPe2
Screening of specific binding peptide targeting blood vessel of human esophageal cancer in vivo in mice
2005
Zhi M et al. Chin Med J (Engl). 2011 Feb 124(4):581-5.
US2010/0233161A1

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
2-month-old Balb/c mice with human esophageal tumor xenograft, fresh human esophageal cancer tissue in immunosuppressed Balb/c mice
Phage display library
M13 phage/C7C peptide library
Additional Detail Fields 2 fields
2-month-old Balb/c mice with human esophageal tumor xenograft, fresh human esophageal cancer tissue in immunosuppressed Balb/c mice
M13 phage/C7C peptide library