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Peptide record

TPDB42667

Clone G3-A28 Anticancer Tumor-homing Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB42667
Clone G3-A28
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 15-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
PKMTLQRSNIRPSMP
Physicochemical Analysis
C74H130N24O21S2
ADCEGHFWYV
P
1756.11
12.41
3
0
4
+3
4.03
-0.993
52.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
5
Residue Composition
number
0
A
2
R
1
N
0
D
0
C
0
E
1
Q
0
G
0
H
1
I
1
L
1
K
2
M
0
F
3
P
2
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 1 K: 1 M: 2 F: 0 P: 3 S: 2 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
15
C74H130N24O21S2
1756.11
12.41
+3
4.03
-0.993
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Endothelial cell and tumor cell
Targeting
Tumor metastasis
Galectin-3

Source & Reference

TumorHoPe2.0
TumorHoPe2
Peptides specific to the galectin-3 carbohydrate recognition domain inhibit metastasis-associated cancer cell adhesion
2005
Zou J et al. Carcinogenesis. 2005 Feb 26(2):309-18.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human breast cancer cell lines BT549, express detectable levels of galectin-3, BT549trans express galactein 7
Phage display library
f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library
Additional Detail Fields 2 fields
Human breast cancer cell lines BT549, express detectable levels of galectin-3, BT549trans express galactein 7
f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library