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Peptide record

TPDB42665

P18-2 Anticancer standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB42665
P18-2
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 7-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Cyclized N-terminal: Cyclized
Sequence
PIPRPIF
Physicochemical Analysis
C42H66N10O8
ANDCEQGHLKMSTWYV
P
839.05
11.05
1
0
3
+1
0.41
0.357
111.43
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
0
L
0
K
0
M
1
F
3
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 0 M: 0 F: 1 P: 3 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
7
C42H66N10O8
839.05
11.05
+1
0.41
0.357
Cyclized
L
Cyclic
Cyclized
Anticancer
Analogue of Phakellistatin 18
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 = 79.71 µM
Anticancer
79.71 µM

Target

Lung Cancer
A-549
Lung

Assay & Model

Cytotoxicity assay
Not Available

Source & Reference

CancerPPD 2.0
CancerPPD2
2018

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 >100 µM
Anticancer
100 µM

Target

Cervical Cancer
BEL-7042
Cervix

Assay & Model

Cytotoxicity assay
Not Available

Source & Reference

CancerPPD 2.0
CancerPPD2
2018