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Peptide record

TPDB42657

Anticancer Tumor-homing Peptides standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB42657
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia TumorHoPe2.0
standard
No
A 6-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia and TumorHoPe2.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acetylation
Sequence
Ac-PHSCNK-NH2
Physicochemical Analysis
C27H44N10O9S1
ARDEQGILMFTWYV
NCHKPS
684.77
8.97
2
0
0
+1
2.71
-1.750
0.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
3
Residue Composition
number
0
A
0
R
1
N
0
D
1
C
0
E
0
Q
0
G
1
H
0
I
0
L
1
K
0
M
0
F
1
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 0 K: 1 M: 0 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C27H44N10O9S1
684.77
8.97
+1
2.71
-1.750
Amidation
Acetylation
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
Melanoma
Integrins

Source & Reference

TumorHoPe2.0
TumorHoPe2
Peptide PHSCNK as an integrin ?Ä??(5)?Ä??(1) antagonist targets stealth liposomes to integrin-overexpressing melanoma.
2012
Dai W et al. Nanomedicine. 2012 Jan 31.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
B16F10 cells overexpressing integrin
Male C57BL/6 mice
Synthetic
Liposomes loaded doxorubicin
Additional Detail Fields 3 fields
Liposomes loaded doxorubicin
B16F10 cells overexpressing integrin
Male C57BL/6 mice