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Peptide record

TPDB42636

L8 Anticancer standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB42636
L8
Anticancer
Cancer-related peptides
ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF pep-lab
standard
No
A 18-aa standard natural anticancer peptide sequence curated from ACP740 _ACP240, AntiCP 2.0, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
PAWAKAFRAAARMKLKAA
Physicochemical Analysis
C90H148N28O19S1
NDCEQGHISTYV
A
1958.40
12.43
5
0
12
+5
-0.09
-0.017
66.11
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
5500
280.84
0
Residue Composition
number
8
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
3
K
1
M
1
F
1
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 8 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 3 M: 1 F: 1 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
18
C90H148N28O19S1
1958.40
12.43
+5
-0.09
-0.017
Free
L
Cyclic
Free
Antimicrobial
Lactoferrin
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50=110 µM
Anticancer
110 µM

Target

Skin Cancer
Meth A
Skin

Assay & Model

MTT/MTS assay
4-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2002

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50=87 µM
Anticancer
87 µM

Target

Breast Cancer
MT-1
Breast

Assay & Model

MTT/MTS assay
4-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2002
Evidence 3 Activity

Activity

IC50
IC50=180 µM
Anticancer
180 µM

Target

Colon Cancer
HT-29
Colon

Assay & Model

MTT/MTS assay
4-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2002