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Peptide record

TPDB42635

P264-G274 Anticancer standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB42635
P264-G274
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 11-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
PARDVLNTTSG-NH2
Physicochemical Analysis
C46H79N15O18
CEQHIKMFWY
T
1130.22
6.78
1
1
3
-0
2.67
-0.536
70.91
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
4
Residue Composition
number
1
A
1
R
1
N
1
D
0
C
0
E
0
Q
1
G
0
H
0
I
1
L
0
K
0
M
0
F
1
P
1
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 1 S: 1 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
11
C46H79N15O18
1130.22
6.78
-0
2.67
-0.536
Amidation
L
Linear
Free
Anticancer
Parasporin-2Aa1
Evidence Records 2 records
Evidence 1 Activity

Activity

EC50
EC50 = 90.98 ± 0.75 µM
Anticancer
90.98

Target

Colorectal Cancer
SW-480
Colon

Assay & Model

Sulforhodamine B assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

EC50
EC50 = 11.28 ± 0.52 µM
Anticancer
11.28

Target

Colorectal Cancer
SW-620
Colon

Assay & Model

Sulforhodamine B assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021