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Peptide record

TPDB42614

Anticancer Tumor-homing Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB42614
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 20-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
NRLKCRAQATHSAAPCIRGY
Physicochemical Analysis
C92H154N34O26S2
DEMFWV
A
2216.57
10.42
5
0
7
+4
3.14
-0.595
59.00
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
1615
72.86
7
Residue Composition
number
4
A
3
R
1
N
0
D
2
C
0
E
1
Q
1
G
1
H
1
I
1
L
1
K
0
M
0
F
1
P
1
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 4 R: 3 N: 1 D: 0 C: 2 E: 0 Q: 1 G: 1 H: 1 I: 1 L: 1 K: 1 M: 0 F: 0 P: 1 S: 1 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
20
C92H154N34O26S2
2216.57
10.42
+4
3.14
-0.595
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing (Phage display clone)
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Selection of tumor-binding ligands in cancer patients with phage display libraries
2006
Krag DN et al. Cancer Res. 2006 Aug 1 66(15):7724-33.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
Phage display library
M13 phage/Random 20 mer (X4CX10CX4) peptide library
phage display library for clones recovery only
Additional Detail Fields 2 fields
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
M13 phage/Random 20 mer (X4CX10CX4) peptide library