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Peptide record

TPDB42608

Anticancer Tumor-homing Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB42608
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 20-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
NNRACFRTSKGNPAECPYLG
Physicochemical Analysis
C92H144N30O29S2
DQHIMWV
N
2198.46
9.06
3
1
5
+2
3.63
-0.925
29.50
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
1615
73.46
8
Residue Composition
number
2
A
2
R
3
N
0
D
2
C
1
E
0
Q
2
G
0
H
0
I
1
L
1
K
0
M
1
F
2
P
1
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 2 N: 3 D: 0 C: 2 E: 1 Q: 0 G: 2 H: 0 I: 0 L: 1 K: 1 M: 0 F: 1 P: 2 S: 1 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
20
C92H144N30O29S2
2198.46
9.06
+2
3.63
-0.925
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing (Phage display clone)
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Selection of tumor-binding ligands in cancer patients with phage display libraries
2006
Krag DN et al. Cancer Res. 2006 Aug 1 66(15):7724-33.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
Phage display library
M13 phage/Random 20 mer (X4CX10CX4) peptide library
Additional Detail Fields 2 fields
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
M13 phage/Random 20 mer (X4CX10CX4) peptide library