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Peptide record

TPDB42607

Loop1-PS2Aa Anticancer standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB42607
Loop1-PS2Aa
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 11-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
NNETYFNAVKP-NH2
Physicochemical Analysis
C58H85N15O19
RDCQGHILMSW
N
1296.40
6.87
1
1
4
-0
2.69
-1.155
35.45
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
1490
114.93
5
Residue Composition
number
1
A
0
R
3
N
0
D
0
C
1
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
1
F
1
P
0
S
1
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 3 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 1 P: 1 S: 0 T: 1 W: 0 Y: 1 V: 1
Chemical Descriptors
11
C58H85N15O19
1296.40
6.87
-0
2.69
-1.155
Amidation
L
Linear
Free
Anticancer
Parasporin-2Aa1
Evidence Records 2 records
Evidence 1 Activity

Activity

EC50
EC50 = 23.76 ± 1.25 µM
Anticancer
23.76

Target

Colorectal Cancer
SW-480
Colon

Assay & Model

Sulforhodamine B assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

EC50
EC50 = 106.2 ± 1.67 µM
Anticancer
106.2

Target

Colorectal Cancer
SW-620
Colon

Assay & Model

Sulforhodamine B assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021