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Peptide record

TPDB42584

ΔM4 Anticancer standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB42584
ΔM4
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 20-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
NFFKRIRRAWKRIWKWIYSA
Physicochemical Analysis
C133H197N39O24
DCEQGHLMPTV
R
2726.27
12.42
7
0
11
+7
-3.26
-0.765
68.50
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
17990
659.87
3
Residue Composition
number
2
A
4
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
3
I
0
L
3
K
0
M
2
F
0
P
1
S
0
T
3
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 4 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 0 K: 3 M: 0 F: 2 P: 0 S: 1 T: 0 W: 3 Y: 1 V: 0
Chemical Descriptors
20
C133H197N39O24
2726.27
12.42
+7
-3.26
-0.765
Free
L
Linear
Free
Anticancer
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 9.31 µM
Anticancer
9.31 µM

Target

Skin Cancer
A-375
Skin

Assay & Model

Not Available

Source & Reference

CancerPPD 2.0
CancerPPD2
2020

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.