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Peptide record

TPDB42581

Rapeseed peptide Anticancer standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB42581
Rapeseed peptide
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 7-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
NDGNQPL
Physicochemical Analysis
C30H48N10O13
ARCEHIKMFSTWYV
N
756.77
3.10
0
1
1
-1
2.55
-1.743
55.71
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
0
R
2
N
1
D
0
C
0
E
1
Q
1
G
0
H
0
I
1
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 1 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
7
C30H48N10O13
756.77
3.10
-1
2.55
-1.743
Free
L
Linear
Free
Anticancer
extracted from rapeseed protein
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 = 1.56 mmol/L
Anticancer
1.56 mm

Target

Liver Cancer
HepG-2
Liver

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

28.39 ± 0.80% apoptosis rate at 0.5 mmol/L
Anticancer

Target

Liver Cancer
HepG-2
Liver

Assay & Model

Apoptosis assay

Source & Reference

CancerPPD 2.0
CancerPPD2
2023