Back to search

Peptide record

TPDB42579

U7 Anticancer standard
11 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB42579
U7
Anticancer
Cancer-related peptides
CancerPPD 2.0 dbACP
standard
No
A 11-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0 and dbACP, with an available 3D structural model.
Sequence
NCSIHGDIPAY
Physicochemical Analysis
C51H76N14O17S1
REQLKMFTWV
I
1189.31
4.94
1
1
4
-1
1.23
-0.091
80.00
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
1490
125.28
4
Residue Composition
number
1
A
0
R
1
N
1
D
1
C
0
E
0
Q
1
G
1
H
2
I
0
L
0
K
0
M
0
F
1
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 1 C: 1 E: 0 Q: 0 G: 1 H: 1 I: 2 L: 0 K: 0 M: 0 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
11
C51H76N14O17S1
1189.31
4.94
-1
1.23
-0.091
Free
L
Linear
Free
Anticancer
Phoenix dactylifera
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 554 µM
Anticancer
554 µM

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2024

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 584 ± 29.99 µM
Anticancer
584

Target

Breast Cancer
T-47D
Breast

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2024
Evidence 3 Activity

Activity

IC50
IC50 = 523 µM
Anticancer
523 µM

Target

Liver Cancer
HepG-2
Liver

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2024