TPDB

3D PDB MODEL

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TPDB ID TPDB42570

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

dbACP

Sequence_Type

standard

Has_Modification No

Description A 208-aa standard natural anticancer peptide sequence curated from dbACP, with an available 3D structural model.

Sequence

MVPVLAADGAAVELADTTLLAPTTFEVGPGERWCVTGGNGTGKTTLLRAFAGTRSLTAGSVSVRGEPVAMTDPRHRRLMASLVEPVPVARDMTLREQVALVAASWYGNSTAAAEGTGRVVERLGLSALGERFPHQVSSGQSQLFSLALTLVRPADVVLLDEPERHLDRHRVDLVAGLLAERAEAGTAFLVATHDPALVAACDGRVELG

FASTA

>TPDB42570|Anticancer|length=208
MVPVLAADGAAVELADTTLLAPTTFEVGPGERWCVTGGNGTGKTTLLRAFAGTRSLTAGSVSVRGEPVAMTDPRHRRLMASLVEPVPVARDMTLREQVALVAASWYGNSTAAAEGTGRVVERLGLSALGERFPHQVSSGQSQLFSLALTLVRPADVVLLDEPERHLDRHRVDLVAGLLAERAEAGTAFLVATHDPALVAACDGRVELG

Formula C952H1551N281O292S6

Absent Amino Acids I

Common Amino Acids A

Mass 21797.86

PI 5.45

Basic Residues 24

Acidic Residues 24

Hydrophobic Residues 93

Net Charge -5

Boman Index 42.84

Hydrophobicity 0.138

Aliphatic Index 98.51

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 12615

Absorbance 280nm 57.87

Polar Residues 37

number

30

A

18

R

2

N

10

D

2

C

14

E

4

Q

20

G

5

H

0

I

27

L

1

K

4

M

5

F

11

P

11

S

17

T

2

W

1

Y

24

V

Amino Acid Distribution

A: 30 R: 18 N: 2 D: 10 C: 2 E: 14 Q: 4 G: 20 H: 5 I: 0 L: 27 K: 1 M: 4 F: 5 P: 11 S: 11 T: 17 W: 2 Y: 1 V: 24

Length

208

Formula

C952H1551N281O292S6

Mass

21797.86

PI

5.45

Net Charge

-5

Boman Index

42.84

Hydrophobicity

0.138

Evidence 1 Activity

Source & Reference

Database Source dbACP