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Peptide record

TPDB42539

Anticancer standard
3057 amino acids
Basic Information
3D PDB MODEL
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TPDB42539
Anticancer
Cancer-related peptides
dbACP
standard
No
A 3057-aa standard natural anticancer peptide sequence curated from dbACP, with an available 3D structural model.
Sequence
MTMARLMTDLADAGVTLRRRGDQLQVQAPQGALDAALVARLREAKEELLRVLDDEGARAAPLAPAQPGEAGDAAALSPGQARLVAATRLGDPAMYNEQAAIELADAVDAEAVARAFAALARRHDILRTVFSDGEPVRQTVLPEPIVTLQAWTVDGDDALRARAADLARLPFAAGAPMWRVDLFSTPERAAVLVLTIHHAIFDRWSMSVLIRDFSAYLALPDAAEAPASGLSYRDYSAWQRRWMASPDYAAQLDAWVDDLAEVDEVPAIRGDRPRPPAMSGRGGTERFEIPADCMDAAAAFSRSRNTTLFTTLFSAFALLQHRYTGEARALTLTPAANRPFQAAEEIAGYFVNLVALATEVGEGDSFGALVDRARDASARAFARQGVPLDAIVERLRARGGPRHEQFAQTVFAFQNVRLPAVRTASGAAVPFDLDSPFARFDLYLSIEGDERGTFAVWQYNTDLYEAATIRQLGEHYLALLRAALASPDADARALPILSAEEEARLRGWGRHELPYRADAAIDRLFRERAADHPGRVALEQGGVRWTYAELDQWSDRAAGALRAAGVEAGAVVGVAGERSPRLLAAFLAVLKAGAAYLPLDPTYPAARLRAMTADAAPALMIIADGLDAGWLGDYAGPVLSLADCEAGVARPLQSEARPAEAESLAYVMYTSGSTGQPKGVAVPHRAVARLATGGGYARLDASTVMLQQSPLGFDASTFEIWGCWLNGGRLVVAEPGMPFLDAASRDGVTTMWLTADLFRMAVEEEPAALGGLRELLTGGDALPVASCRAFLEACPGVALINGYGPTENTTFTCSHRVTAGDARRGSIPIGRPIGNTEVRVVDAGGRLVPVGVPGELWAGGDGLALGYLGRADLTAERFVAAPPPDGGRWYRTGDRVRWRRDGVLEFLGRIDEQIKLRGYRIELGEIEATLGHYPGLSGCAVALRRSAADEKQLVGYLVARPDSGEAADSAAVQAWLEARLPGYMVPRVWVWLDALPQSANGKVDRKRLPDPVVETGAAAAETEAEAALVEIWQGLLGLERVGVRDNFFALGGDSILSIQMASRAAERGLRLSPQQVFRYPTIAELAAEGCAAEEAGAQAEQGEVVGEVRPGPIQAWYLDWPGTDWEQFNQGAYLGLDGVVDAESLIGALQAVAQRHDALRIGWRRDGERWIQASGAGEPVEVKAVDLRGLADAEAALERDAAALQSSLRLGGASLWAARLYRLDEGWRLLWLAHHASVDGVSWRILLEDLWRAYAALSRGEAAAWPAKTVSYQAWSQRLWEWAETLPDSTLSYWREMDAPGMPLPGFNAAEDTVAAESRVSLQWEPETTERWLRQAGEAYRMRPEELLVTALARALRQWTGAEECVLDLEGHGRDGLAGVDVSRTVGWFTSLYPLRLPLSGELSGDLKRVKERMRSVPDGGLAYHALRYGGRGSALGGHARTVCFNYLGQWRLEEGGEPRSTWLGEPPGGTRGAGMTRRYGLDVVAQVHEGRLRVDWLYSAARQREDAIKALAEGFRAELDAVLAHCQSPESGGLTPSDLPLAHLDQSEIDAIEREHPRLEALYGLTPLQQGILFHSIADDGAPLYVEQLHWKMSGAFDAERFRQAWFDVAAAHAALRTTFRWRGLKSAVQIVHPRLDPDWETLDWGDVSADACASRFAALCELHRERGFDLERGPLLRGTLVREPGDAWRFLWSYHHAVVDGWSVPLILKQVLGRYAELGAGEAAPLPGSRFLPFVNWLAARDAREQAEYWKQVLEGIEEPTPIGFASPARGPQAQGQGRRAFVFDAALREQVDRAARRAGVTRASLLTGAWALTLGYAGGGRDVVFGTTLSGRPATLPGVERMVGLFINTVPVRVGMDDDASVSQWLRQLHEQQSERARLGAASLTDIQRWAGYEGGELLSSLFVVENYPVDRTLARGDAGFDVSEFAAAETRTNYPLVGQLIPGEETVLYVDFDASRYDEESIGRLGASFMHLLSQLAAQPDARLGDLTLVDDDEARRLIHDWNATPPVGEGYLLHASIERHAELTPLAPAIIGVDEAMNYRELADETLRTARAVAAAGAKREPVAVLLPRSARAVAAYSGVMRAGCAYVPADPAMPPGRLRDLLATVGYVLTTREHLPMLDGVAARAILIDETPPADVALPDAAPDDLAYVMFTSGSTGKPKGVMITHRAASLTIEVFLRRYEIGASDRLMCVSAAGFDLSVFDFFGAFAAGAAVLLAPESSTIAPAVWLELMTREGATVWESVPAVMELLLLECRQSGRALPPSLKLAMLSGDRVPVGLPAQIRAAATSDPEVLALGGATEGAIWSCWYDTRELASDAAFVPYGRHLPGQRLYVLSSSLQAVPVGVPGDLWIAGAGVALGYLGQPDLTAYRFVDNPFVPGERMYRTGDRARVLADGNLEFLGRVDDQVKIGGFRIEIGEIEAALAAAPGVERGVASVVERDGRRIIAGYVLLLPGASLDLAAVRDALARRLPPYMLPASIMALDSLPLSANGKVDRKRLPDPVVETGAAAAETEAEAALVEIWQGLLGLERVGVRDNFFALGGDSILSIQMASRAAERGLRLSPQQVFRYPTIAELAAEGCAAEEAGAQAEQGEVVGEVRPGPIQAWYLDWPGTDWEQFNQGAYLGLDGVVDAESLIGALQAVAQRHDALRIGWRRDGERWIQASGAGEPVEVKAVDLRGLADAEAALERDAAALQSSLRLGGASLWAARLYRLDEGWRLLWLAHHASVDGVSWRILLEDLWRAYAALSRGEAAAWPAKTVSYQAWSQRLWEWAETLPDSTLSYWREMDAPGMPLPGFNAAEDTVAAESRVSLQWEPETTERWLRQAGEAYRMRPEELLVTALARALRQWTGAKECVLDLEGHGRDGLAGVDVSRTVGWFTSLYPLRLPLSGELSGDLKRVKERMRSVPDGGLAYHALRYGGRGSELGGHARTVCFNYLGQWRLEEGGEPRSTWLGEPPGGTRGAGMTRRYGLDVVAQVHEGRLRVDWLYSAARQREDAIKALAEGFRAELDAVLAHCQSPESGGLTPSDLPLAHLDQNDIDEVLQLLNEQL
Physicochemical Analysis
C14725H23022N4234O4360S67
A
331276.55
4.87
354
410
1411
-97
531.80
-0.122
91.18
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
587950
177.48
503
Residue Composition
number
473
A
280
R
30
N
192
D
21
C
218
E
103
Q
292
G
45
H
78
I
360
L
29
K
46
M
80
F
167
P
147
S
122
T
85
W
80
Y
209
V
Amino Acid Distribution
A: 473 R: 280 N: 30 D: 192 C: 21 E: 218 Q: 103 G: 292 H: 45 I: 78 L: 360 K: 29 M: 46 F: 80 P: 167 S: 147 T: 122 W: 85 Y: 80 V: 209
Chemical Descriptors
3057
C14725H23022N4234O4360S67
331276.55
4.87
-97
531.80
-0.122
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbACP