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Peptide record

TPDB42528

Anticancer standard
3518 amino acids
Basic Information
3D PDB MODEL
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TPDB42528
Anticancer
Cancer-related peptides
dbACP
standard
No
A 3518-aa standard natural anticancer peptide sequence curated from dbACP, with an available 3D structural model.
Sequence
MTEQSAVGLPLTPAQESLWFAHQSRPLDAGFLIAEYVDIEGELDLTTLRRAVASVARETEALRTTITDAPDGGTAGQRVHDGMALDVPLVDLSASANGEADAHRAMLQDLATPVDVTRGPVTALVLYRLSTSRHLLYLRTHHLVLDGYGAAAALGRIATTYGLLATGEEVTAEPLPLEPLVADARQYARSAEYAEDGAYWRESLAGAPHAERLTDRTGPPGTEVLRRSVALDPARWRRLREGARQGRVAWPALFVAGTAAYTHRMRGAHDLLLGMPVTGRRSRIARRTPGMTSQIVPLRLRLDPAVPVRDLLRQVTTAMRGALRHQRFPVEELRRELGLGRGDSLVGPAVNVLAFDENLRFGPATGTLHNLSLGPVEDLTLAVHPAPGGAGARVDVLANAALYDGTSAAGHLERILRLTEEFAADPDRPLSALELTGPEERDRVLALGTGPRERSRIPAPRTDAPVDGGVDGRPGPATAPTEHAGSTEHADVPEPTLPEVLARLARETPDAPAVDDGTRGLTFAELDRAVDAAASALRADGAGPGTTVAVALPRSVDTVVAPLAVLRSGAVYLPVDVTYPAERIAHLLADAAPVVLLCAPGGPVAGMAPAGTAVRSLSRSGTTAPGAPFDGPRAEDAAYLFYTSGSTGRPKGVLVEHRSISNLLAHHRRESHASAESAGGRRLRVALTASTSFDASWDPLLWMLGGHHLHIADDTTRRDPEALVAFLRAERIDVIETTPSFLGQLLAAGLTAETPTADGADGAPVHRPTVIALGGEPVGDELWQRLSSQPGLLAYNFYGPTETTVDAVTARVRGTDPVIGRPVRGARAYVLDTALRLLPYGATGELYLAGEGVARGYTGRPGPTADRFLADPFGEPGSRMYRTGDLARWHENGSLEFAGRSDTQIKIRGQRVETGEIEAALAALPGIAQAAVALHADGPAGETLAAYLVPTPDEAGDGVRRDRRRVRDALAASLPAYMVPAAYAATDRLPLTPNGKLDTAALPRATAVSTGPKSPPRTATERAVCAAVADLLGLADVGRDDDFFSLGGHSLLATGLLADLAGRTGVRLPVRALFEAPTVAGLAARVDAGRRSAGPEDPPGGRAVAERPARLPLSAAQHRLWLLEHMGEGGDRYHIPVAVRLDGDLDVPALRAAFSDLLARHESLRTVYPQDAEGPHQVVLPAGGCGVELRTAPVLPDARPEDVPAPRFELAERPPVHAVLVPTAEPAGDGPGSHLLLLTLHHIVTDGWSMGPLVHDLCAAYRARTGGHAPRWQPLPAQYADYALRQRARLGDREDPGSLAARQLAASRAALEGLPPELPLPHDRPRPERATARGGRVPVRLDAADHRALGALAREAGVSPFMVLHGVLATLLHRLGGGDDIVVGTPVAGRDEEEFHDVVGFFVNTLVLRVGVGGDPTFRELLDRVRETDLSAYGRQDLPFEQLVEALAPPRSLSRHPLFQVMLALNNTPAPRLDLPGVHAEPLRSGRTTAKFDLTWDFTETHDAHGRPDGLTGEVEYSAELFDESTVRRFAGHFVRLLRSVLRSPDARLGALGMLTEDQRLAALDTGARDDSAERGDELVHSVCDVLETQAAVTPDRTAVAEGRRTVSFGELATGLRDTARLLAAAGVRPGDRVAVALPRSARQIAAVFGVLRAGAVYVPLDPAHPAARNARILESARPALLLTERERAAALPASRTPTLYLDEAPDAAPAAEALPADGPRGADPAYVLYTSGSTGRPKGVVVEHRALANLLRHHGRHLIEPAERANNGRPLRVALTAAATFDASWDPLLWMVAGHELHLVDDASRHDPEALVRILHERRIDVLETTPSFLEQLRVCGLFAPGRPWPRVVALGGEPVHEKLWRELAELSGVSVWNLYGPTETTVDSVIAPVTAGTGPAIGHAVTGMRARVLDSRLGPTPPGVTGELYLAGAGVARGYDGATGLTADRFLADPYGPAGSRMYRTGDLVRRRPDHSLVFVGRTDSQVKVRGFRVETGEVEAALTAHPAVRRAVVTVRQAEGGGRLVAWAVPETGARPTPAGLRAFLGDRLPAYMTPSHLALVPEIPLTAHGKTDFGRLPDPAPALAEQGERPRTPQEEILCALFAECLGTDSVGRDADFFALGGHSLLATRVVNRVRSAFGAEIPVRALFEDPTPAGLARHLDGAARGRPSLHARADRPAELPLSFAQRRLWFLNRMRPDDASYNLPMAVSLCGRLDVAALHGALGDVVARHESLRTVFREAADRSGTPVQRVLSPGAARPALTVTPSTPDQVAGLLREAARAGFDLGGDLPLRAELLRTGADEHVLLLTVHHIAADGWSMGPLAQDLAAAYAARVAGRAPDWTPLPVQYADYALWQRDLLGGHDDPDSVYARQLAYWRGALADAPTETALPADRPRPDAGSGLGGSVPLPLSGSDGRRLAELARREGASTFMALHAVLAALLDRYGAGDDVVVGSPVAGRTDEALAGLVGFFVNTLALRVRTDGDPDFRALLERARETDLAAYAHQDLPFESLVEHLAPPRSPARHPLFQVMLSLNNAGRPALDLPGLHAEVRGVDTDAAKFDLSFSFSEQSGDGELTGQLEFARDLFDTATAQDLADSFVALLRLVVADPDSPLSRHDPLDASRLAGPLGHGDGPQAAPRHPTVVAGFAATAAAARSSDIAVRCGAQALSFAELARDGARLAHLLRGRGVDADRTVAVLLPRSTGSLTALLGVLAAGGAYAPLDDALPPARVAAVLSDARPAVVLATAATADRIPDGPWQTVLLDSPGTWAELAALPAEFPDGAAPGPRDPAYVVHTSGSTGRPKGVVVEHRSLAQLAEHHRRTLFDPARAATGRHRLRVALTASLSFDAAWDPVLWMLDGHELLVVDNDTRRDPAALVRAVREERVDVLETTPSHAAALLDAGLCAEGSPGHRPAVLALGGEDVPPGLWRRLREVPGLTVWNLYGPTEATVDTLYARLDRGDRPELGEPVAGTSCYVLDRLLRPAAPNTTGELYLSGASLARGYLGRPAETAARFVPDPFGPPGGRMYRTGDLVRRTADGRLEFRGRADGQVKVRGFRVEPGEIVTALEAQPGVRRAAVALRPVGSGAAHGTEQLVAYVVPGDGPGASGGPAAPDRDALRAALAAELPGYMVPAAFVVLDALPLTASGKLDAGALPAPRGEHLAHAAGRAPSGPREDLLCALFAETLDVERCWSDDDFFTLGGHSLLAARLLARVREATGVELGIRELFEAPTPAGLATALTAREAEAGTGTGPGADLACLLPLRSGGSLPPLFCVHPAGGLAWPYAGLLQHVADRPVYGLQTPNLDGTEHFPDSIEAMAAYYVDQLRTVQPHGPYRLLGWSFGGNVVQEIAVRLQEAGEEVALLSIMDAFPVPPADGLEDAGHDVVFRALLTALGVDLSAWDADAPLDAAVVRDALRESGSPLGALEPAAIETMVGNFADQARLMRRHVPRTFRGDVLFFRATEEDPASGLVPSLWDPYVDGALVVHDVPCGHAQMLRPDARAVVGPVLDAALRAT
Physicochemical Analysis
C16432H26157N4897O4907S50
A
372432.32
5.69
461
438
1527
-70
739.70
-0.111
92.09
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
284850
76.48
529
Residue Composition
number
545
A
346
R
29
N
248
D
17
C
190
E
61
Q
339
G
102
H
41
I
444
L
13
K
33
M
88
F
289
P
145
S
212
T
34
W
65
Y
277
V
Amino Acid Distribution
A: 545 R: 346 N: 29 D: 248 C: 17 E: 190 Q: 61 G: 339 H: 102 I: 41 L: 444 K: 13 M: 33 F: 88 P: 289 S: 145 T: 212 W: 34 Y: 65 V: 277
Chemical Descriptors
3518
C16432H26157N4897O4907S50
372432.32
5.69
-70
739.70
-0.111
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbACP