Peptide record

TPDB42522

Anticancer Antifungal standard
114 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB42522
Anticancer Antifungal
Anti-infective peptides Cancer-related peptides
dbACP Antifungipept CAFPdb dbAMP Peptipedia
standard
No
A 114-aa standard-residue multi-activity (Anticancer and Antifungal) peptide sequence curated from dbACP, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
MTCKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKKENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMARLTWASHEKMHEGDEGPGHHHKPGLGEGTP
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C579H909N163O179S7
E
13241.99
5.68
22
20
36
-5
2.24
-0.870
68.42
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
6990
0.53
25
Residue Composition
number
3
A
3
R
7
N
6
D
1
C
14
E
5
Q
8
G
8
H
6
I
11
L
11
K
6
M
5
F
4
P
4
S
7
T
1
W
1
Y
3
V
Amino Acid Distribution
A: 3 R: 3 N: 7 D: 6 C: 1 E: 14 Q: 5 G: 8 H: 8 I: 6 L: 11 K: 11 M: 6 F: 5 P: 4 S: 4 T: 7 W: 1 Y: 1 V: 3
Chemical Descriptors
114 reviewed residue count
C579H909N163O179S7 sequence-only estimate (linear, free termini)
13241.99 sequence-only estimate (linear, free termini)
5.68 sequence-only estimate (linear, free termini)
-5 sequence-only estimate (linear, free termini)
2.24 sequence-only estimate (linear, free termini)
-0.870 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP dbACP CAFPdb Antifungipept