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Peptide record

TPDB42509

MzDef Anticancer standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB42509
MzDef
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 34-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
MSSSNCANVCQTENFPGGECKAEGATRKCFCKNC
Physicochemical Analysis
C143H229N45O51S7
DHILWY
C
3619.08
7.63
4
3
7
+1
8.88
-0.550
17.35
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
375
10.36
16
Residue Composition
number
3
A
1
R
4
N
0
D
6
C
3
E
1
Q
3
G
0
H
0
I
0
L
3
K
1
M
2
F
1
P
3
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 1 N: 4 D: 0 C: 6 E: 3 Q: 1 G: 3 H: 0 I: 0 L: 0 K: 3 M: 1 F: 2 P: 1 S: 3 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
34
C143H229N45O51S7
3619.08
7.63
+1
8.88
-0.550
Free
L
Linear
Free
Antimicrobial and Anticancer
Zea mays L.
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 ~ 22 µg/mL
Anticancer
22 µg/mL

Target

Liver Cancer
HepG-2
Liver

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 14.85 µg/mL
Anticancer
14.85 µg/mL

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020
Evidence 3 Activity

Activity

IC50
IC50 = 29.85 µg/mL
Anticancer
29.85 µg/mL

Target

Colon Cancer
HCT-116
Colon

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020