TPDB

3D PDB MODEL

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TPDB ID TPDB42508

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

dbACP

Sequence_Type

standard

Has_Modification No

Description A 313-aa standard natural anticancer peptide sequence curated from dbACP, with an available 3D structural model.

Sequence

MSSPADHTTVIVGAGPAGLTAALGLARYRHPVIVVDSPRAPRNSASAGVHGHIGMDGVTPDEFRARAWRELSRYRTVERLEDEVDSVSTAPGGGFRITLGSGGSVESATVLLATGVLDVHPSGVDGFAECWGRSVIHCPFCLGEENAGGSWATLADNAHLAGLSAVAFRAWSEDTIAICPESMPGLDTARATARSGGGGDVVTGTVRRLHHRQGALYGIELADGRILERQTLVWTPPQRQQPLVQRAADELKLTVDDAGFIGVDDSQCTSVPGLYAAGDLTSRWKQSVTASTAAGAAAADAIHMSALLSAVHQ

FASTA

>TPDB42508|Anticancer|length=313
MSSPADHTTVIVGAGPAGLTAALGLARYRHPVIVVDSPRAPRNSASAGVHGHIGMDGVTPDEFRARAWRELSRYRTVERLEDEVDSVSTAPGGGFRITLGSGGSVESATVLLATGVLDVHPSGVDGFAECWGRSVIHCPFCLGEENAGGSWATLADNAHLAGLSAVAFRAWSEDTIAICPESMPGLDTARATARSGGGGDVVTGTVRRLHHRQGALYGIELADGRILERQTLVWTPPQRQQPLVQRAADELKLTVDDAGFIGVDDSQCTSVPGLYAAGDLTSRWKQSVTASTAAGAAAADAIHMSALLSAVHQ

Formula C1413H2240N424O445S9

Absent Amino Acids

Common Amino Acids A

Mass 32576.44

PI 5.57

Basic Residues 36

Acidic Residues 34

Hydrophobic Residues 128

Net Charge -8

Boman Index 56.65

Hydrophobicity -0.045

Aliphatic Index 85.18

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 39210

Absorbance 280nm 120.36

Polar Residues 68

number

44

A

23

R

3

N

20

D

5

C

14

E

9

Q

36

G

11

H

11

I

26

L

2

K

4

M

6

F

15

P

25

S

22

T

6

W

4

Y

27

V

Amino Acid Distribution

A: 44 R: 23 N: 3 D: 20 C: 5 E: 14 Q: 9 G: 36 H: 11 I: 11 L: 26 K: 2 M: 4 F: 6 P: 15 S: 25 T: 22 W: 6 Y: 4 V: 27

Length

313

Formula

C1413H2240N424O445S9

Mass

32576.44

PI

5.57

Net Charge

-8

Boman Index

56.65

Hydrophobicity

-0.045

Evidence 1 Activity

Source & Reference

Database Source dbACP