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Peptide record

TPDB42506

Anticancer Tumor-homing Peptides standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB42506
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 6-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
N-terminal: N -terminal modification for pentameric form
Sequence
MSRTMS
Physicochemical Analysis
C26H49N9O10S2
ANDCEQGHILKFPWYV
MS
711.85
11.05
1
0
2
+1
0.75
-0.500
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
2
M
0
F
0
P
2
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 2 F: 0 P: 0 S: 2 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C26H49N9O10S2
711.85
11.05
+1
0.75
-0.500
N -terminal modification for pentameric form
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting & further studied
Human breast and ovarian adenocarcinomas
ErbB-2

Source & Reference

TumorHoPe2.0
TumorHoPe2
Selection of peptides and synthesis of pentameric peptabody molecules reacting specifically with ErbB-2 receptor
2001
Houimel M et al. Int J Cancer. 2001 Jun 1 92(5):748-55.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
SK-BR-3, MDA-MB-468, OVCAR5
Phage display library
Additional Detail Fields 1 fields
SK-BR-3, MDA-MB-468, OVCAR5