TPDB

3D PDB MODEL

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TPDB ID TPDB42496

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

dbACP

Sequence_Type

standard

Has_Modification No

Description A 165-aa standard natural anticancer peptide sequence curated from dbACP, with an available 3D structural model.

Sequence

MSNSKVYFDIDIDGQDAGRIVFELFEDVTPRTAKNFIELSTGEHGFGYAGSSFHRVIPQFMLQGGDFTAGNGTGGKSIYGAKFEDENFKLKHTEPYLLSMANAGPNTNGSQFFITTVVTSWLDGKHVVFGKVVEGTEVVDKIEGYGSSPQGTTSAKITVRASGKL

FASTA

>TPDB42496|Anticancer|length=165
MSNSKVYFDIDIDGQDAGRIVFELFEDVTPRTAKNFIELSTGEHGFGYAGSSFHRVIPQFMLQGGDFTAGNGTGGKSIYGAKFEDENFKLKHTEPYLLSMANAGPNTNGSQFFITTVVTSWLDGKHVVFGKVVEGTEVVDKIEGYGSSPQGTTSAKITVRASGKL

Formula C799H1219N209O248S3

Absent Amino Acids C

Common Amino Acids G

Mass 17816.90

PI 5.43

Basic Residues 19

Acidic Residues 19

Hydrophobic Residues 61

Net Charge -4

Boman Index 31.38

Hydrophobicity -0.259

Aliphatic Index 68.48

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 12950

Absorbance 280nm 72.68

Polar Residues 44

number

9

A

4

R

7

N

9

D

0

C

10

E

5

Q

22

G

4

H

9

I

8

L

11

K

3

M

13

F

5

P

13

S

14

T

1

W

5

Y

13

V

Amino Acid Distribution

A: 9 R: 4 N: 7 D: 9 C: 0 E: 10 Q: 5 G: 22 H: 4 I: 9 L: 8 K: 11 M: 3 F: 13 P: 5 S: 13 T: 14 W: 1 Y: 5 V: 13

Length

165

Formula

C799H1219N209O248S3

Mass

17816.90

PI

5.43

Net Charge

-4

Boman Index

31.38

Hydrophobicity

-0.259

Evidence 1 Activity

Source & Reference

Database Source dbACP