TPDB

3D PDB MODEL

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TPDB ID TPDB42493

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

dbACP

Sequence_Type

standard

Has_Modification No

Description A 575-aa standard natural anticancer peptide sequence curated from dbACP, with an available 3D structural model.

Sequence

MSLAFNVGVTPFSGQRVGSRKEKFPVQGFPVTTPNRSRLIVNCSLTTIDFMAKMKENFKREDDKFPTTTTLRSEDIPSNLCIIDTLQRLGVDQFFQYEINTILDNTFRLWQEKHKVIYGNVTTHAMAFRLLRVKGYEVSSEELAPYGNQEAVSQQTNDLPMIIELYRAANERIYEEERSLEKILAWTTIFLNKQVQDNSIPDKKLHKLVEFYLRNYKGITIRLGARRNLELYDMTYYQALKSTNRFSNLCNEDFLVFAKQDFDIHEAQNQKGLQQLQRWYADCRLDTLNFGRDVVIIANYLASLIIGDHAFDYVRLAFAKTSVLVTIMDDFFDCHGSSQECDKIIELVKEWKENPDAEYGSEELEILFMALYNTVNELAERARVEQGRSVKEFLVKLWVEILSAFKIELDTWSNGTQQSFDEYISSSWLSNGSRLTGLLTMQFVGVKLSDEMLMSEECTDLARHVCMVGRLLNDVCSSEREREENIAGKSYSILLATEKDGRKVSEDEAIAEINEMVEYHWRKVLQIVYKKESILPRRCKDVFLEMAKGTFYAYGINDELTSPQQSKEDMKSFVF

FASTA

>TPDB42493|Anticancer|length=575
MSLAFNVGVTPFSGQRVGSRKEKFPVQGFPVTTPNRSRLIVNCSLTTIDFMAKMKENFKREDDKFPTTTTLRSEDIPSNLCIIDTLQRLGVDQFFQYEINTILDNTFRLWQEKHKVIYGNVTTHAMAFRLLRVKGYEVSSEELAPYGNQEAVSQQTNDLPMIIELYRAANERIYEEERSLEKILAWTTIFLNKQVQDNSIPDKKLHKLVEFYLRNYKGITIRLGARRNLELYDMTYYQALKSTNRFSNLCNEDFLVFAKQDFDIHEAQNQKGLQQLQRWYADCRLDTLNFGRDVVIIANYLASLIIGDHAFDYVRLAFAKTSVLVTIMDDFFDCHGSSQECDKIIELVKEWKENPDAEYGSEELEILFMALYNTVNELAERARVEQGRSVKEFLVKLWVEILSAFKIELDTWSNGTQQSFDEYISSSWLSNGSRLTGLLTMQFVGVKLSDEMLMSEECTDLARHVCMVGRLLNDVCSSEREREENIAGKSYSILLATEKDGRKVSEDEAIAEINEMVEYHWRKVLQIVYKKESILPRRCKDVFLEMAKGTFYAYGINDELTSPQQSKEDMKSFVF

Formula C2975H4651N793O897S25

Absent Amino Acids

Common Amino Acids L

Mass 66680.93

PI 5.07

Basic Residues 78

Acidic Residues 86

Hydrophobic Residues 237

Net Charge -16

Boman Index 138.23

Hydrophobicity -0.357

Aliphatic Index 87.13

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 77405

Absorbance 280nm 116.08

Polar Residues 159

number

31

A

34

R

30

N

34

D

10

C

52

E

26

Q

25

G

8

H

35

I

58

L

36

K

15

M

31

F

12

P

39

S

32

T

8

W

22

Y

37

V

Amino Acid Distribution

A: 31 R: 34 N: 30 D: 34 C: 10 E: 52 Q: 26 G: 25 H: 8 I: 35 L: 58 K: 36 M: 15 F: 31 P: 12 S: 39 T: 32 W: 8 Y: 22 V: 37

Length

575

Formula

C2975H4651N793O897S25

Mass

66680.93

PI

5.07

Net Charge

-16

Boman Index

138.23

Hydrophobicity

-0.357

Evidence 1 Activity

Source & Reference

Database Source dbACP