TPDB

3D PDB MODEL

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TPDB ID TPDB42491

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

dbACP

Sequence_Type

standard

Has_Modification No

Description A 600-aa standard natural anticancer peptide sequence curated from dbACP, with an available 3D structural model.

Sequence

MSILRNRTATAAIVAVAAGALTLTACGGGDSDSSSKDNSKQKEDAKSQSKPVQIGDAQASTGPAPDVEGAKSGGVATVYQATDFSHLDPGQIYVSDGKLLSRLIFRGLTQYDEDENGNLTVVGDLATDAGKESDGGKTWTYTLKDNLKDENGNPINSADFRNTVERLYSNYITDGPTFLQQWLSGDGTTYRDAYQGPDKGKHLPDDVLETPDDKTIVFHFDTPRPDLPQMLTMPGYQLVPEETDTKEKYDSAPVSVGPYKISDFKPGKSMTLVKNTQWDPKSDSVRHQYLDGFNISMNHDDEDQTKTLLADQGEAKNAMMFTGQVATTQLQKVVGDKQAMENRTIQGYAPYVWQLNFNMDRIKDKKLRDAISLALPSDAVFKADGGAYGGEVANSLMSPTTPGYDEKFDPFNREKKPNGDVEAAKKLIKEGGFEGKSLVYAYGNTPERQKQAVLIATALEKIGLDIQKKEIDSATWYEQVGKVKNGYDLYMTGWGQDWPSASTVFPPVYDGTQIQDGASNYSHINDDHVNSEIKRIQKITDTDEATKAWAELNEYISKEVNPAAPIYYTKVFQIFGSNIGGIRYSSDSSYVDVTRVFLKK

FASTA

>TPDB42491|Anticancer|length=600
MSILRNRTATAAIVAVAAGALTLTACGGGDSDSSSKDNSKQKEDAKSQSKPVQIGDAQASTGPAPDVEGAKSGGVATVYQATDFSHLDPGQIYVSDGKLLSRLIFRGLTQYDEDENGNLTVVGDLATDAGKESDGGKTWTYTLKDNLKDENGNPINSADFRNTVERLYSNYITDGPTFLQQWLSGDGTTYRDAYQGPDKGKHLPDDVLETPDDKTIVFHFDTPRPDLPQMLTMPGYQLVPEETDTKEKYDSAPVSVGPYKISDFKPGKSMTLVKNTQWDPKSDSVRHQYLDGFNISMNHDDEDQTKTLLADQGEAKNAMMFTGQVATTQLQKVVGDKQAMENRTIQGYAPYVWQLNFNMDRIKDKKLRDAISLALPSDAVFKADGGAYGGEVANSLMSPTTPGYDEKFDPFNREKKPNGDVEAAKKLIKEGGFEGKSLVYAYGNTPERQKQAVLIATALEKIGLDIQKKEIDSATWYEQVGKVKNGYDLYMTGWGQDWPSASTVFPPVYDGTQIQDGASNYSHINDDHVNSEIKRIQKITDTDEATKAWAELNEYISKEVNPAAPIYYTKVFQIFGSNIGGIRYSSDSSYVDVTRVFLKK

Formula C2911H4513N781O948S12

Absent Amino Acids

Common Amino Acids D

Mass 66004.24

PI 4.72

Basic Residues 73

Acidic Residues 87

Hydrophobic Residues 213

Net Charge -20

Boman Index 154.81

Hydrophobicity -0.665

Aliphatic Index 67.97

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 85720

Absorbance 280nm 129.87

Polar Residues 174

number

46

A

17

R

28

N

58

D

1

C

29

E

31

Q

51

G

7

H

28

I

38

L

49

K

11

M

18

F

30

P

41

S

45

T

8

W

28

Y

36

V

Amino Acid Distribution

A: 46 R: 17 N: 28 D: 58 C: 1 E: 29 Q: 31 G: 51 H: 7 I: 28 L: 38 K: 49 M: 11 F: 18 P: 30 S: 41 T: 45 W: 8 Y: 28 V: 36

Length

600

Formula

C2911H4513N781O948S12

Mass

66004.24

PI

4.72

Net Charge

-20

Boman Index

154.81

Hydrophobicity

-0.665

Evidence 1 Activity

Source & Reference

Database Source dbACP