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Peptide record

TPDB42480

Anticancer standard
3274 amino acids
Basic Information
3D PDB MODEL
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TPDB42480
Anticancer
Cancer-related peptides
dbACP
standard
No
A 3274-aa standard natural anticancer peptide sequence curated from dbACP, with an available 3D structural model.
Sequence
MSEARLLRRPVSAAQSGIWVAQHLHADSPLYNCGGYYEIAGPVDAEIFAEAVRRGVQETEALRSRFAQEERDTDSGPEVTLHQLVEPAEPHPLRFVDLRAASDPEAAAHRWMNARMARPFDLTRGPVSEQALLTLADDLHWYFHGYHHAVLDGFGQSVYATRVAALYSALLAGEEPSPTGFATLDRVVADEAAYAGSRRHTRDRAHWREVFTDLPEPVSLGRASGSTHSLRRHVRTLPTPLAERLPGAAARLGVQWPALALAATAAFFHRMTGGTDFTFSIPLAGRSGRTSLTTPSAMVNVLPLRVRLTSDIRFTELAAQVSRSLADVVRHQRFRGEELIHELGLSGAGQARLGPTVNIMAFAGEPLFGTTPAVTHPLSTGPVNDLKINFYGTADSRTGIRVELDGHHELYGADELAAHCDRLVRVLEWVADSDDESRVSEVEVLEEAEREQILSGWQGASRPVRGASLPQLIAEQAERTPDAVAVECGDRVLTYGELDAWSARTAGWLQGQGVGRGTFVAVKLPRSVELIVALLAVTKTGAAYVPVDPEYPAERVAHILSDATPALVIDDTAMLKQETGKPFDGVRIDPHDPVYVIYTSGSTGRPKGVVVEHASVGAYLERAREVYPDASGTALLHSSVAFDLTVTALYTPLVSGGRVILTDLDEHAATTGQPTFMKVTPSHLGLLEALPDEISPSGTLITGGEALLGEALASWRATHPDVTVINAYGPTEATVNCTDFHIQPGEPVPSGPVPIGRPFWNTRAYVLDHRLRPVPPGVTGELYVAGIVLARGYHNRPDLTAERFTADPYGPPGTRMYRTGDTARWTHTGQLTYTGRTDDQIKLRGFRIELGEIQAVLMTHPHITQAAVIVREDQPGDQRLTAYTVNTVGTDTTTDDLAAHTAAHLPAYMIPSHFITLDQLPLTPNGKLDRNALPTPEYNQHTSEGRAPRTPHEQALCTLFADVLGTDTVTIDDDFFHLGGHSLLATTLISRIRTTIGAELPIRQLFETPTVAGISATLDQQPARAAVRRPGVTAGPRPGRIPVSYAQQRLRFLSLLEDGSTAYNAPGALRLTGALDQEALRQALADVVTRHESLRTVFAEDESGFTQVILEPYEVALGLDVVAVDEERLAARLAEAARYSFDLAAEPPLRATLFEVGDDEYVLLLLLHHIAGDGSSMRPLARDLAAAYAARVRGATPEWAPLPVQYADYSLWQRDILGTEDDPTSEITRQLDYWTHTLTGLPDQLELPYDRPRSEVVTQHGGQVSLRIPAELHGQLHELARTTRSSLFMVFQAGLAALLTRLGAGTDIPLGSPIAGRTDAAVEELVGFFANTLVLRTDTSGDPTFAELVERVRARSLEAYQHQDLPFERLVEAVNPERSLTRHPLFQVCLTLHNTDPRATVAEEARLPGLAVELERLPIEDTKFDLNWELTEHVDGLGRPAGVTVDLEFSAELFDRGTARSVADRFVRLLSATARDVEVPIGEIDVLAPGERTEILDEWSDATRPPVAAALSGSSLPRTADDTRAYVLDDTLVPVPPGVVGQLYVTGSGPAGDAAEQERWLPCPYGRAGWMYRTGTSARWSADGELRLVEVPGRTPVGPADVWPARSRGPRSPREQILCTVFAELLGVASVGIDDDFFDRGGHSLSAVRLLSRIRAVLGVELSIRRLFENPTVAGVVEALDEASGARRPVTAVARPARIPLSYAQQRLWFLNHLEGPSATYNIPVALGLKGALDRAALRLALTDVVARHESLRTLFAEDSEGARQIVLPAAHATPELIEVDVAPGELPGRIRAAASHPFDLATELPVRAWLFSAHDGERVLVLVVHHIAGDGWSMGPLARDLSLAYTARARGDAPAWTPLPVQYADYTLWQREVLGSEDDPDSEISRQLAHWKTALADLPEELELPVDRPRPARQSHRGGRVPFEVSAGLHARLAAFARETGTSLFMVAQAALAALLTRLGAGTDIPIGSPVAGRTDAAVEDLVGFFVNTLVLRTDTSNDPTFAELVGRVRETNLGAYGHQDVPFERLVEVLSPVRSLARHPLFQVLLGFDNNQEALEILRLPGLTVDVHAPETGRAKFDLAFFFDERYGPHGEPEGLGGAVEYNSDLFDRSTAQEFAERLLRVLEGAVADPERPIGRLEVMSPAERDRVVDEWNRTAHDVPPLPVPTLFERQVAAEPRATAVLGEDVTLSYAELNSRANRLARLLAASGVGAEDVVAIALPRSADLVVALVAALKTGAAYLTLDVSAPEQRLRAVLTDCGPRVVVTDLATRPLLGDGIALDVVLDAPETVRELAAGADADLTDADRVRPLDLRHPAYVVYTSGSTGTPKGVVMPMSSLVNLLAWHTGTYCGGVGTLTAQFLAVSFDFAVQEILQALVVGKTLVIPEEHVRRDAYELAQWIARYSINELFAPTLVIDAVLAAAADTGERLDSLTDLFQGGEQFRLSHELREFCASGWRRMAHNIYGPAETHAATTATLPGDIDEWPTAASIGQPLWNASVYVLDAGLRPVPPGVRGELYIGGAQLARGYLGRPDRTAERFVASPFGRPGARLYRTGDVVRWNHCGELEFLGRADHQVKIGGFRVEPGEVEAVLADHPSVETAVVVTREESAGPTRLVAYVVPEGQDADPALGRTLRAHLEQQLPHYMVPSFVVPLDELPLTANGKLDRRALPAPGSDTVAAEPRTEREKVLCGLVADVLGLAEVGVDDGFFDLGGDSIMSIQLVSRARRAGLQLSVRDVFEHRTVAALAEIVTETDTTVTEEPGAGIGDVPLTPIKRWLLARTDDLDAFNMSAVLRVPADVDADALTGAVQALLDHHDALRARLTPAPQRRLEVREPGSVDAGALVRRVDASGADGADLHALVREAGAAARDRLHLGEGRVVQAVWFDRGRDSAGMLLLIIHHLVVDGVSWRILIPDLAEAYEAVSAGRKPALQPVGTSLRRWSQRLTEEAVKPAWVADAAWWQDVLRSAGPPPGRRPLDPARDRQATAGRLTVTLPTEVTEAVLTRVPAAFHAEVNDVLLTAFALAWARWRPGGPELLLDLEGHGREEHLVEGADLSRTVGWFTNLYPVRLDTGGVDLARAFAGGSAAGSAAKRIKEQLRSVPDKGMGYGLVRHLNPATAAGFDGHAAPHVAFNYLGRFTAADCDRAADWTPVTGFDAVAGDPPQLPLAHPLELNSRTEDGPEGSELVAFWTWAEEILDEDEVRELAELWFQALRALVTHSENPHAGGLTPSDVSLSSIGQDEIEAFEEELDDLFDDFDDEPHDFETEEEASK
Physicochemical Analysis
C15759H24797N4503O4767S39
A
354866.90
4.89
398
453
1409
-141
737.11
-0.135
93.52
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
367685
103.61
600
Residue Composition
number
415
A
277
R
44
N
223
D
14
C
230
E
90
Q
261
G
95
H
88
I
381
L
26
K
25
M
101
F
222
P
155
S
228
T
48
W
69
Y
282
V
Amino Acid Distribution
A: 415 R: 277 N: 44 D: 223 C: 14 E: 230 Q: 90 G: 261 H: 95 I: 88 L: 381 K: 26 M: 25 F: 101 P: 222 S: 155 T: 228 W: 48 Y: 69 V: 282
Chemical Descriptors
3274
C15759H24797N4503O4767S39
354866.90
4.89
-141
737.11
-0.135
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbACP