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Peptide record

TPDB41929

hP2 Anticancer standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB41929
hP2
Anticancer
Cancer-related peptides
ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF
standard
No
A 25-aa standard natural anticancer peptide sequence curated from ACP740 _ACP240, AntiCP 2.0, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
MRGIRGADFQAFQQARAVGLAGTFR
Physicochemical Analysis
C119H190N40O32S1
NCEHKPSWY
A
2725.13
12.40
4
1
12
+3
1.12
-0.100
62.80
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
5
A
4
R
0
N
1
D
0
C
0
E
3
Q
4
G
0
H
1
I
1
L
0
K
1
M
3
F
0
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 5 R: 4 N: 0 D: 1 C: 0 E: 0 Q: 3 G: 4 H: 0 I: 1 L: 1 K: 0 M: 1 F: 3 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
25
C119H190N40O32S1
2725.13
12.40
+3
1.12
-0.100
Free
L
Linear
Free
Antiangiogenesis
Human endostatin peptides
Evidence Records 1 records
Evidence 1 Activity

Activity

19% inhibition at 7 mg/kg/d
Anticancer

Target

Pancreatic Cancer
BxPC-3
Pancreatic

Assay & Model

Matrigel Assay
672-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2005

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.