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Peptide record

TPDB41922

Sample Peptide 2 from EP3604345B1 Anticancer standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB41922
Sample Peptide 2 from EP3604345B1
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 29-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
MQIPQAPWPVVWAVLQLGWRRKKRRQRRR-NH2
Physicochemical Analysis
C168H275N59O34S1
NDCEHFSTY
R
3697.47
13.18
9
0
12
+9
3.99
-1.069
77.24
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
16500
446.25
4
Residue Composition
number
2
A
7
R
0
N
0
D
0
C
0
E
4
Q
1
G
0
H
1
I
2
L
2
K
1
M
0
F
3
P
0
S
0
T
3
W
0
Y
3
V
Amino Acid Distribution
A: 2 R: 7 N: 0 D: 0 C: 0 E: 0 Q: 4 G: 1 H: 0 I: 1 L: 2 K: 2 M: 1 F: 0 P: 3 S: 0 T: 0 W: 3 Y: 0 V: 3
Chemical Descriptors
29
C168H275N59O34S1
3697.47
13.18
+9
3.99
-1.069
Amidation
L
Linear
Free
Anticancer
Synthetic
Evidence Records 3 records
Evidence 1 Activity

Activity

Cell Viability
Cell Viability = 3.6% at 25 µM
Anticancer

Target

Lung Cancer
NCI-H2444
Lung

Assay & Model

CCK-8 / WST-8
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023
EP3604345B1

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

Cell Viability
Cell Viability = 4.9% at 25 µM
Anticancer

Target

Lung Cancer
HCC-827
Lung

Assay & Model

CCK-8 / WST-8
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023
EP3604345B1
Evidence 3 Activity

Activity

Cell Viability
Cell Viability = 9.1% at 25 µM
Anticancer

Target

Lung Cancer
A-549
Lung

Assay & Model

CCK-8 / WST-8
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023
EP3604345B1