TPDB

3D PDB MODEL

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TPDB ID TPDB41889

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

dbACP

Sequence_Type

standard

Has_Modification No

Description A 308-aa standard natural anticancer peptide sequence curated from dbACP, with an available 3D structural model.

Sequence

MPGQELRTVNGSQMLLVLLVLSWLPHGGALSLAEASRASFPGPSELHSEDSRFRELRKRYEDLLTRLRANQSWEDSNTDLVPAPAVRILTPEVRLGSGGHLHLRISRAALPEGLPEASRLHRALFRLSPTASRSWDVTRPLRRQLSLARPQAPALHLRLSPPPSQSDQLLAESSSARPQLELHLRPQAARGRRRARARNGDHCPLGPGRCCRLHTVRASLEDLGWADWVLSPREVQVTMCIGACPSQFRAANMHAQIKTSLHRLKPDTVPAPCCVPASYNPMVLIQKTDTGVSLQTYDDLLAKDCHCI

FASTA

>TPDB41889|Anticancer|length=308
MPGQELRTVNGSQMLLVLLVLSWLPHGGALSLAEASRASFPGPSELHSEDSRFRELRKRYEDLLTRLRANQSWEDSNTDLVPAPAVRILTPEVRLGSGGHLHLRISRAALPEGLPEASRLHRALFRLSPTASRSWDVTRPLRRQLSLARPQAPALHLRLSPPPSQSDQLLAESSSARPQLELHLRPQAARGRRRARARNGDHCPLGPGRCCRLHTVRASLEDLGWADWVLSPREVQVTMCIGACPSQFRAANMHAQIKTSLHRLKPDTVPAPCCVPASYNPMVLIQKTDTGVSLQTYDDLLAKDCHCI

Formula C1485H2415N467O430S14

Absent Amino Acids

Common Amino Acids L

Mass 34140.22

PI 9.96

Basic Residues 52

Acidic Residues 28

Hydrophobic Residues 114

Net Charge +13

Boman Index 67.29

Hydrophobicity -0.363

Aliphatic Index 89.71

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 32470

Absorbance 280nm 95.11

Polar Residues 74

number

30

A

35

R

6

N

14

D

9

C

14

E

14

Q

16

G

12

H

6

I

46

L

5

K

5

M

4

F

27

P

29

S

13

T

5

W

3

Y

15

V

Amino Acid Distribution

A: 30 R: 35 N: 6 D: 14 C: 9 E: 14 Q: 14 G: 16 H: 12 I: 6 L: 46 K: 5 M: 5 F: 4 P: 27 S: 29 T: 13 W: 5 Y: 3 V: 15

Length

308

Formula

C1485H2415N467O430S14

Mass

34140.22

PI

9.96

Net Charge

+13

Boman Index

67.29

Hydrophobicity

-0.363

Evidence 1 Activity

Source & Reference

Database Source dbACP