TPDB

3D PDB MODEL

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TPDB ID TPDB41868

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

dbACP

Sequence_Type

standard

Has_Modification No

Description A 164-aa standard natural anticancer peptide sequence curated from dbACP, with an available 3D structural model.

Sequence

MNYSSYLLASWLCVMLGYSQATIAEDLGTLMEYFQNGSTSSDISDNGTLFLNMMDRWKEDGDKKILMSQIVTVYFKIFEIFKNNTVIKKSVENIKEDMIMKFFTNNTASKVNDFESVINTQVNDLRVQKKAIFELALIMNDLSNKPHLRKRKRRQNRKQGEIKQ

FASTA

>TPDB41868|Anticancer|length=164
MNYSSYLLASWLCVMLGYSQATIAEDLGTLMEYFQNGSTSSDISDNGTLFLNMMDRWKEDGDKKILMSQIVTVYFKIFEIFKNNTVIKKSVENIKEDMIMKFFTNNTASKVNDFESVINTQVNDLRVQKKAIFELALIMNDLSNKPHLRKRKRRQNRKQGEIKQ

Formula C848H1357N229O253S10

Absent Amino Acids

Common Amino Acids K

Mass 19129.09

PI 9.66

Basic Residues 25

Acidic Residues 19

Hydrophobic Residues 67

Net Charge +5

Boman Index 35.20

Hydrophobicity -0.438

Aliphatic Index 83.78

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 18450

Absorbance 280nm 96.45

Polar Residues 51

number

6

A

7

R

15

N

10

D

1

C

9

E

8

Q

6

G

1

H

13

I

14

L

17

K

9

M

9

F

1

P

13

S

9

T

2

W

5

Y

9

V

Amino Acid Distribution

A: 6 R: 7 N: 15 D: 10 C: 1 E: 9 Q: 8 G: 6 H: 1 I: 13 L: 14 K: 17 M: 9 F: 9 P: 1 S: 13 T: 9 W: 2 Y: 5 V: 9

Length

164

Formula

C848H1357N229O253S10

Mass

19129.09

PI

9.66

Net Charge

+5

Boman Index

35.20

Hydrophobicity

-0.438

Evidence 1 Activity

Source & Reference

Database Source dbACP