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Peptide record

TPDB41844

Anticancer standard
3159 amino acids
Basic Information
3D PDB MODEL
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TPDB41844
Anticancer
Cancer-related peptides
dbACP
standard
No
A 3159-aa standard natural anticancer peptide sequence curated from dbACP, with an available 3D structural model.
Sequence
MNHTARGMMRTPALSTGLARAVHERAGLTPHAPAVSDGGRTLDYAALDAEAAGAAAALRALRVGPGDAVAVALPRSWQLVCVMLGVLRLGARVVPVDLQSPAERRDHVLADSGAVVHVHTGDAPHGLPPGVAAVPVDGLLRDGRDAVDRPSPPDTAPPVSFVFYTSGTTGRPKGVEVRDAGILRLARPGYLRLEETERFACLANPAFDALSFEVWVPLLTGGCCVVLADDDVQSPERLAEVLLRERVDTAFVTAALFNAVVATVPDCFAGLGQLLIGGEQLNARAVRSWYRHNAGSGTRLYNGYGPTECSTFALCHPIPRDLDTPVVPIGRTLPETGATLVVPGTTREAAPGEVAELLLSGAGLAAGYRNLPEESARRFVPLSRPDGPPVVHYRTGDLVRRDARGDIEYIGRADRQVKVRGFRIEPGELEQRILAHPAVRQAHVCTRRAGGDGPNELLAYLVVDSALTWAEFDRHLAAHLPAYMRPHHLYRIDAVPRTANGKADQAALLARTDPPWRPDGDAAEVTDPVQRELLEMAGRVLGLPDLRPGDTWIACGGDSLTALRLRFEIRRRWNRDLPQSLVLRGDLAALAEAVRAAPDTDAPGYPSASAAGAGSAPATSEQQRLWLIQQQSPHSRAYDVRLAFAVEGDVDVPALRRASSRLVARHPALRTAFEAAPEGLLQVVGEPYDPWVPAERPYASPGVVAGGVPDPGAPQGAFFAEPFDLSRPRMLRMGLLPAESGSGSVLLLHLHHIAVDGWSVNVLLRDLSDGYAAALAGGEDAPDRAAPAPTPLDFAVWQEQWRAEPAYDALRTGLLAHYADRTEPGRAVPQPAPHLADRPGAALLHTQLDVVRRAALDRLCGAAGLTRFQVLLAVYAWALYGVTGDARPRVAAPVAGRPVREFEDSVGMFANTVLLPLDVSPRRELRQELLRLGRDTQEVLERQDVALADVVQGQGPLRRAGSPFDFLFVLENTDFDSLELPGCETSPRWPVPAGAKCPVTLSVIERPDGLACQWEYAPEHFTPERAAALAELFRRGVDALAEEHSATGTVADLVAGHRGSLPEPGRGESRAWAWTTVAEGFALQVARTPSDPALMTAEGPVDYRTLDAWAAALAADLRATAGARDAEGPCHVALFLEPSVEHVVALLALARLNLTAVPVDPSYPPALLRQILEQTDPLCVLLPPGDQSAFDAVDPRGRLGLPRRTVTLSAAPDPALPDPPHRGERPLYTLFTSGSTGTPKGVRVYDRTLCNLLQWQAASGGLGGAAATQQFSMLSFDVSFQEIFGTLCSGGCLHLVRPGLRQDVPALLDRLEAAGIERLFLPFVALQMLAEHAVHLGRYPSRLREVVTAGEQLVCTDAVRRWFAGMPGSRLFNQYGPTETHVVSSLCLDGDPSRWPERPAIGGPVANAVLHVVDEAGLPVPPGCPGDLLLGGVIDAPCYLGDGRLNEERFTELPGQGLFYRSGDRARFDSDGLLHFLGRADDQVKLSGHRLEPGQVEAALLRHPAVVGAVVAVDGGELVACLRCGDAAPSPAELREHLAGLLPAHVRVARYRLLAELPRTPSGKLDREAALRAPSRELPGAHRAADGPSSGREAALAAAFEEATGSAIGPDQTYFEAGASSLDLMRFHLRCTTVLGLPLTVADLFEHVTVRRLARFLDTDAGAGTGGGAGAGMSTGTATSTSVGAGTGDHAGAAAGAGAGDLTGAAAGAEGIAVVGMAVRAPGAPDLAAFWELIASGAGGIEYFDAPEGIVGARSQMDGLLAFDPERFGISRQEARLMDPQQRHLLMACVEALAHAGLADTGAARVGLVAGAGENTYFQAMLREADPAHLPDGFQLALHHDKDFLATKAAYHLGLTGPVLAAQTACSSSLVAVHLAAGMLRQGDADVMLAGGVLVDTSLSQGYRYRPQHILSADGHCRPFSDDADGTVGGSGTGVLVLKPLSRARADGDTVYAVITGSAVNNDGSAKLGYSAPSLAGQRAAVRTALRRSGRPGSDVAYVEAHGTGTRLGDPVEAEALRQALGTTEPDHCALTSVKSQIGHLGAAAGAVGLIRAVLSVHHGVIPPTRGFRALNPEIGPDPTPFYVPTEALPWPARRDRVAAVSSFGIGGTNAHVVLEGGSAAGPPDAADSGAADQEVVPLVVLSAAGAVRLRSDASRIADYLERRPEAYGQVLRHLQAGRPQERLRAAAVCPTPLSAVDWLRAAAASSAEPGAGERPAAPPRDPVAAAECRSVSELADAWLAGRTVAWPEGSAQAPWDFPPPSFDLADFHFGRASAAHSAPAPSGAPAAAPSGALAAARTPERLPEAQWLHQPQWVRLRRAATVPRGDRARTLVVVAEGPADAALVDAFAAGHRRVVWVRASADRARTGADRFEADPADPAHLRYVLDAVTEDGPPGVDWVHMLPLSVDGPVHATSVDRAAWACLDTPAALLRAVSGRPYAALLRPWWVSRGARPVHGDVSRPETALLAGVTEVGPQEGAPRGHWVDLPGTGPWAAQLAALFAEPETAGLPRQLALRQGCWWEQVLLPVAAAPDHEGEPLPASEGDHLILGGTGGLGTGIAAWLLAHTPGRVLLLSRRPRLPEVLAPWAERVELVDADLAVEPTAEVAVRIASRTTGLASVVHAAGVAAGGLVARRDAEDMRKALAPKLRGALLVEQLIEEHRPALAVYCSSMSAHLGGVGQFDYAAANALLDAFARYGGPGGGTTARSALAWDVWRETGMAVRTLHSDARHRAHLGVGLTVDEGQRVFARAVGLGLPHLLVSTTDVEESRVFYEGAGHDASDVPAARLPGAPAGDRAPAPDSARELLAEQLCILLGVDRLDPDASLYDLGADSLTLLSVIEAVDRSFGVELDLGSLSHRVSLDEIVARLDEARGEADRTQDSQDHLNPEEGKDEDGDEVTLTVWQQGAGRDVVCLVHPVGGDVQAYRFLAAALDPGATVALIADPGLRGRELPRWTIAERAHHYLAALRARFPETTWRWHLAGWSFGAWVAAGMAAEAESAGRPARSLHLLDPPPPGSGSVFQEYDERQLKTVFAAELGLGGEETGPGRQADTYADRLTRCCLANVHSMAAHRLPRITVTATRLWLARDPVEGLPSLGTPGEQRARWRAHLPEPTAAEVLDTTHYGVVRPPHAAAVAHAVNEAVHEAVAEGSTGGSAAR
Physicochemical Analysis
C14712H23217N4359O4380S66
A
333355.72
5.54
388
376
1382
-75
615.92
-0.078
90.07
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
359325
107.79
506
Residue Composition
number
505
A
278
R
27
N
203
D
38
C
173
E
85
Q
313
G
94
H
43
I
363
L
16
K
28
M
77
F
249
P
149
S
152
T
50
W
55
Y
261
V
Amino Acid Distribution
A: 505 R: 278 N: 27 D: 203 C: 38 E: 173 Q: 85 G: 313 H: 94 I: 43 L: 363 K: 16 M: 28 F: 77 P: 249 S: 149 T: 152 W: 50 Y: 55 V: 261
Chemical Descriptors
3159
C14712H23217N4359O4380S66
333355.72
5.54
-75
615.92
-0.078
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbACP