TPDB

TPDB ID TPDB41837

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

CancerPPD 2.0

Sequence_Type

modified_plain

Has_Modification Yes

Description A 192-aa modified anticancer peptide sequence curated from CancerPPD 2.0, without an available 3D structural model.

Modification

Modified, details unspecified

Sequence

MNFQQRLQSLWTLARPFCPPLLATASQMQMVVLPCLGFTLLLWSQVSG<BR>AQGQEFHFGPCQVKGVVPQKLWEAFWAVKDTMQAQDNITSARLLQQEVLQ<BR>NVSDAESCYLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANNF<BR>VLIVSQLQPSQENEMFSIRDSAHRRFLLFRRAFKQL

FASTA

>TPDB41837|Anticancer|length=192
MNFQQRLQSLWTLARPFCPPLLATASQMQMVVLPCLGFTLLLWSQVSG<BR>AQGQEFHFGPCQVKGVVPQKLWEAFWAVKDTMQAQDNITSARLLQQEVLQ<BR>NVSDAESCYLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANNF<BR>VLIVSQLQPSQENEMFSIRDSAHRRFLLFRRAFKQL

Formula C964H1506N268O261S9

Absent Amino Acids

Common Amino Acids L

Mass 21314.74

PI 10.05

Basic Residues 24

Acidic Residues 12

Hydrophobic Residues 81

Net Charge +8

Boman Index 18.98

Hydrophobicity -0.111

Aliphatic Index 85.78

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 26720

Absorbance 280nm 125.36

Polar Residues 57

number

12

A

13

R

8

N

4

D

4

C

8

E

19

Q

5

G

4

H

3

I

25

L

7

K

5

M

14

F

7

P

13

S

10

T

4

W

3

Y

15

V

Amino Acid Distribution

A: 12 R: 13 N: 8 D: 4 C: 4 E: 8 Q: 19 G: 5 H: 4 I: 3 L: 25 K: 7 M: 5 F: 14 P: 7 S: 13 T: 10 W: 4 Y: 3 V: 15

Length

192

Formula

C964H1506N268O261S9

Mass

21314.74

PI

10.05

Net Charge

+8

Boman Index

18.98

Hydrophobicity

-0.111

Evidence 1 Activity

Source & Reference

Database Source CancerPPD 2.0

Other

Source Activity Label	Source Definition
Anticancer	CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.