TPDB

TPDB ID TPDB41834

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

CancerPPD 2.0

Sequence_Type

modified_plain

Has_Modification Yes

Description A 196-aa modified anticancer peptide sequence curated from CancerPPD 2.0, without an available 3D structural model.

Modification

Modified, details unspecified

Sequence

MNFQQRLQSLWTLARPFCPPLLATASQMQMVVLPCLGFTLLLWSQVSG<BR>AQGQEFHFGPCQVKGVVPQKLWEAFWAVKDTMQAQDNITSARLLQQEVLQ<BR>NVSDAESCYLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANN<BR>FVLIVSQLQPSQENEMFSIRDSAHRRFLLFRRAF<BR>KQL

FASTA

>TPDB41834|Anticancer|length=196
MNFQQRLQSLWTLARPFCPPLLATASQMQMVVLPCLGFTLLLWSQVSG<BR>AQGQEFHFGPCQVKGVVPQKLWEAFWAVKDTMQAQDNITSARLLQQEVLQ<BR>NVSDAESCYLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANN<BR>FVLIVSQLQPSQENEMFSIRDSAHRRFLLFRRAF<BR>KQL

Formula C970H1518N272O262S9

Absent Amino Acids

Common Amino Acids L

Mass 21470.93

PI 10.22

Basic Residues 25

Acidic Residues 12

Hydrophobic Residues 81

Net Charge +9

Boman Index 19.79

Hydrophobicity -0.132

Aliphatic Index 84.03

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 26720

Absorbance 280nm 124.45

Polar Residues 57

number

12

A

14

R

8

N

4

D

4

C

8

E

19

Q

5

G

4

H

3

I

25

L

7

K

5

M

14

F

7

P

13

S

10

T

4

W

3

Y

15

V

Amino Acid Distribution

A: 12 R: 14 N: 8 D: 4 C: 4 E: 8 Q: 19 G: 5 H: 4 I: 3 L: 25 K: 7 M: 5 F: 14 P: 7 S: 13 T: 10 W: 4 Y: 3 V: 15

Length

196

Formula

C970H1518N272O262S9

Mass

21470.93

PI

10.22

Net Charge

+9

Boman Index

19.79

Hydrophobicity

-0.132

Evidence 1 Activity

Source & Reference

Database Source CancerPPD 2.0

Other

Source Activity Label	Source Definition
Anticancer	CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.