Back to search

Peptide record

TPDB41818

Anticancer standard
3639 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB41818
Anticancer
Cancer-related peptides
dbACP
standard
No
A 3639-aa standard natural anticancer peptide sequence curated from dbACP, with an available 3D structural model.
Sequence
MMEPTARLVLLSPKHLTDLRRRTGDHSDAALATACAIGLSYWATGQSPAGLDLTAATLFGDVLGWADNGGAAPEGWGVAADGRTITLPEGVVPDDAQLALDDLADFPGRPLGTIGPAGPTARLENLARWNDTDADRERPTLMEMFLEQARARPGAVAVVDERRTLTYRELSDRSAQLAHRLRERGLSDEDVVGISLERSADMVVGLLGVLRAGCAFVPLDPHWPAERRAVVAADARVAVQLNASGEPAPHEPEAVPVDLADWRHGDRPTEGPDPTVRGDALAYVIFTSGSTGRPKGAMIRHEAISERLLWQVHEILDFGHDDASLFKAPLSFDISINEIFLPLVCGARLVVLRPGGERDPHHLLGVIAEQRVTFTYLVSSMLDVLLEMAGDTGRLDSLRHVWCGGEVLTPELYERFRTQLDIPLYHGYGPAETTIGVSHVVYRGAAERLSTSIGRANPNTRLYVLDDELRPVPVGVGGELYAGGLLLGRGYVNAPGLTASRFVANPFADDGSRLYRTGDLARFAPDGSLDFLGRADNQIKIRGMRLEIEDVEAGLAEHPGVRHTCVVPKKNTAGGTYLVGYVIPAAGHGSLRPDEVKAWAAEHMVEYMVPTHVVVTDAFPLTANGKLDRQALPEPTVAASAARPPGTENERAVCTAVAAVLQLDEVGTDQDFFRLGGDSILAISLLSALRDAGLYVTARQIFTHSTVGALAAVASREDTAAVDHRDTPTGTVVGPPVVQWLGETTGAIDGFVQSVVLNTPAALTADALDEILTALVRRHPMLRARLVRGDRWGFDIPDEVPAGALWQESDRPLDSCTALATEALDPAGGAMLRAVWRRSARQLVLVAHHMVIDGVSWRVLMEDLATAWRQYASGAPVELPVEGTSFRRWTGLLERAASDADGQYFRRPLPAADEPVGRRALTEDDTVARERIRTVETGAETTAAVLGTVPAAFHAGVGDVLVTALAVALARRRRDLGQDQTFAHLELEGHGREAAFVAPSAGFEPELSRTVGWFTTLFPVVVDPGTAPDLTAPEYLATALKAVKEDLSRVPDNGISYGALRYLNRVAFDAPAPQVLFNYLGRFDAGAPGDWQLAGSTGQLGEKRDPAMRLPRALEFNAVAEPGPDGEYRLVTTVSWPEGLFTDQDIDALAGHFQDALTGLAALERGGHSPADFRPLRLTQADVDDLDGPALRDILPLTPLQEGLYFHSVYDDETAGSYVEQQLLTLDGDVDADRLATAATRLLTLHPGLAARFTALADGRVVSVLESGHHAPFTTLDRPGITDEEIRDLAERDRRAGFDLATGPLMRYTLIRAGAGRHVLVQTVHHIVADGWSVPPMLRTLLAEYHRPGSAHPLGGFPEHVRRLAALDDRESDRVWREQLAGLPGPSLIAEGHTPSDRFADTATTPGIDVDAAARAAGVPLSVAVHSAWALTLGGILHSEDVVFGSTVSGRDADVPGIQNMVGLLINTVPVRARWSADTTAAELLAQVRAHQSAVLPHQHVSLARTARHTGTGPLFDTLVVFDVATDVGALREPGDTLVVTDIVNEGAPHYPLTLVVERTPDGTPRFNAVHDAALLRESQVQDILHTFTRTLTTLLTSPDTPVAAPVPHTARRAPAVAPATLGDLLDAAARRDPAATAVTQCSLDGATRSLTYGELTEAKDGLAAVLRAAGAGPGRLVAVAVPPSVEQVVALTAVTGAGGAYVPLDAAHPDERLEYILADAAPQVVLVDREQRERFTRLLERAGVPARVLVQGDEPAPADDGPASPAGWHDPAYVIYTSGSTGRPKGVVVPHSGVVTLLAHTQADMGFGPDDVWVQFHSFSFDFAVWELWGALAHGGELLVPEYALTRSPVDFHRLVREHRVTVLNQTPSAFHRFIEADRHAGEPLPALRRIVFGGEALDLGRLRDWVDRHGTATPELVNMYGITETTVHVTHRVLTDADFGPGDAPSPIGTPLPGLVVHLLDDRLRPVPPGRVGAVYVAGDQVSLGYLGRPGLTAGRFVADPFTGDGSRMYHTGDLARRTLDGELHFAGRADDQVQLKGFRVEPGEVEAALRDLDGVSDAAVTVADGGDHLVAHVVGRAPGDLTALLAARLPAHMIPGRVLSVDALPLTVNGKLDRKALAERAANAPLPDGALHRTDSGSAAPDGPAVLDTVVRVFAETLPGSTPDADTDFFAAGGDSIVAITLINRARAAGLSVTPRDVFLLKTPRALAEHLTASTPPPATPEPVRREDGPLPPTPIILRQRELGGSLARFAQARTLLAPEGTAFADVERAARAVVAAHPALRLRLRVDHGVWSLRTEADREVTVVRADGTDPTAAADEAASRLDPESGDVAAFSWLAANRTLVVTVHHLAVDAVSWLILLDDLAGALRGTPVPAPTTSYAEYAEALTHRAAHAAPGLGHWTTALQAPTPLPPPEALRETTAVLAPGISDRLTRTAPTALGLGLTELLCGALRTALTRIQPSPTDLAVDLERHGRVPALEHHDYTRTVGWFTAVAPVRLTPHTDPVAAAREVTERRPDEREHVAYGLLRYLNAQTAPLLTARPQVLFNYLGRGAESEAPRLAGGDRGSPYAVEVNAWTDAATGSLHAVFTLAEGIPDTLTAHWLAALEQLADSAATAERTAPVTPLQRGLYFQSQLTGPTGHYVAQSWFTLERRLDTDALADAMAHVIARHPVVGAGFTTDDDGNPVQVLGAGRRVPVRTVEAATDAEAEALRLADRDTGFDPAEPPLVRLTVVRLPGDRDGLLLSYHLLLWDGWSRETVLRDLFDAYEDILAGTPLDTAPATPRFEDHARALAARDPAPAERFWSEHLAPLSGPTLLAGPAPSLSDDLPHALVHTLTAAESERLRETARTHGVTLNSVLTGAFGLLLGAHTGRADAVFGVTVSGREGEGASGVVGVLLNTVPMWTRARPHDTVRAYLTAVQASRVAAMEHEHLGLGEIQRAAGHDTLFDNLFVLQNFLDLDAFAEMNARHGITSVQADDSTHYPFTWVVTPGDRLTVKLEHRDHDAGRARRLLDDYLRVLADLAASDGPLGALPGPAPAPAPGARTDIGTDTVVDRFDRAADRNPRRVALVAHGSTLTFAELRDRSRAVAGVLVRRGIGPETTVGIAVPRSLDSIVALFAVLRTGAAYVPLELDHPDERIAAIVADARPDVILTVGTVAPRLTGDLIELDRPLPEAEPYVTFAPDDPHRLRHPAYIIHTSGSTGKPKGVVTEYAGLTNMLVNHRRRIFEPVLAEHGHRTFRIAHTVSFAFDMSWEELLWLADGHEVHVCDEELRRDAPRLVEYCAEHAVDVVNVTPTYAQQLVAEGLLDDPARRPALVLLGGEAVTPALWRRLAETEGTVGYNLYGPTEYTINTLGVGTFECPDPVVGVAIDNTDVHVLDPWLRPLPDGVPGELYVSGIGIARGYLGQTAQTAHRFVACPFGAPGERMYRTGDLVTRRPDGNLTYLGRTDQQVKIRGHRVELGEVEAVFTAHPAVRFAAAVAQPDPQVDGAHRLAAYLVLDGADLATVAAEVGAGLPDFLRPTHYARVDGIPLTVNGKADTRALPEAKPLGALTTAGERPPATETETTVCEFFAEALDLDDDEVSAVSDFVSLGGHSMLAVRLTGLLRREYGPVITIRDLFTLRTPEAIARHLDDH
Physicochemical Analysis
C17277H27272N4998O5198S45
A
389615.67
5.13
455
478
1581
-136
774.63
-0.083
94.03
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
351185
90.14
616
Residue Composition
number
498
A
308
R
46
N
281
D
14
C
197
E
73
Q
315
G
124
H
82
I
423
L
23
K
31
M
104
F
263
P
130
S
284
T
45
W
69
Y
329
V
Amino Acid Distribution
A: 498 R: 308 N: 46 D: 281 C: 14 E: 197 Q: 73 G: 315 H: 124 I: 82 L: 423 K: 23 M: 31 F: 104 P: 263 S: 130 T: 284 W: 45 Y: 69 V: 329
Chemical Descriptors
3639
C17277H27272N4998O5198S45
389615.67
5.13
-136
774.63
-0.083
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbACP