TPDB

3D PDB MODEL

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TPDB ID TPDB41755

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

dbACP

Sequence_Type

standard

Has_Modification No

Description A 296-aa standard natural anticancer peptide sequence curated from dbACP, with an available 3D structural model.

Sequence

MITLVRRAAALCVLGAALTACGTTAAEVAPRPAPSAPAPSSSASRTPTPTLAPGPGGLTPVFEHGPRTDGTNHGEQDGTRDGKLIALTFDADMTADQGPRAASGERFDNPQLIAALRELKVPATVFMTGRWAEEYPDEARSIGRDRKFEIANHSYSHYAYTDDCYGLPTVAEDDMRADLERAYTAFEKAGVPNPMPYFRFPGGCYDKAALKELSATGVTAVQWDVVSGDAFATDADAVTRQVLDGARPGSVVVMHCTRSAAPVTEEVVRAVVPELRSRGYRFVKVSDLVGAANGRA

FASTA

>TPDB41755|Anticancer|length=296
MITLVRRAAALCVLGAALTACGTTAAEVAPRPAPSAPAPSSSASRTPTPTLAPGPGGLTPVFEHGPRTDGTNHGEQDGTRDGKLIALTFDADMTADQGPRAASGERFDNPQLIAALRELKVPATVFMTGRWAEEYPDEARSIGRDRKFEIANHSYSHYAYTDDCYGLPTVAEDDMRADLERAYTAFEKAGVPNPMPYFRFPGGCYDKAALKELSATGVTAVQWDVVSGDAFATDADAVTRQVLDGARPGSVVVMHCTRSAAPVTEEVVRAVVPELRSRGYRFVKVSDLVGAANGRA

Formula C1370H2153N397O429S11

Absent Amino Acids

Common Amino Acids A

Mass 31402.23

PI 5.34

Basic Residues 36

Acidic Residues 37

Hydrophobic Residues 121

Net Charge -6

Boman Index 66.49

Hydrophobicity -0.251

Aliphatic Index 70.34

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 24660

Absorbance 280nm 78.53

Polar Residues 63

number

46

A

24

R

5

N

21

D

5

C

16

E

5

Q

25

G

5

H

5

I

18

L

7

K

6

M

10

F

23

P

15

S

24

T

2

W

9

Y

25

V

Amino Acid Distribution

A: 46 R: 24 N: 5 D: 21 C: 5 E: 16 Q: 5 G: 25 H: 5 I: 5 L: 18 K: 7 M: 6 F: 10 P: 23 S: 15 T: 24 W: 2 Y: 9 V: 25

Length

296

Formula

C1370H2153N397O429S11

Mass

31402.23

PI

5.34

Net Charge

-6

Boman Index

66.49

Hydrophobicity

-0.251

Evidence 1 Activity

Source & Reference

Database Source dbACP