TPDB

3D PDB MODEL

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TPDB ID TPDB41727

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

dbACP

Sequence_Type

standard

Has_Modification No

Description A 258-aa standard natural anticancer peptide sequence curated from dbACP, with an available 3D structural model.

Sequence

MGGESTTRTAPRGGGAKNTPVGSRRGQRLSGLAVALGMVLFLGGFVWGAVVYRPYTVPTGSMTPTIAAGDRVLAERVSGSDVRRGDVVVFKDAAWADAPMVKRVVAVGGDTVSCCQKGKLQVNGKVIDEPYLPAGTPAEISDFQTVTVPEGRLFLLGDERDNSVDSTAHLTDAAGGTVSRGAVDARVDAVVWPMNGMLERPTGFETLGGLSSPGPLWTVVALVTGGAVLILGGAAYGPVAKRAEASRARRGTEAAGGR

FASTA

>TPDB41727|Anticancer|length=258
MGGESTTRTAPRGGGAKNTPVGSRRGQRLSGLAVALGMVLFLGGFVWGAVVYRPYTVPTGSMTPTIAAGDRVLAERVSGSDVRRGDVVVFKDAAWADAPMVKRVVAVGGDTVSCCQKGKLQVNGKVIDEPYLPAGTPAEISDFQTVTVPEGRLFLLGDERDNSVDSTAHLTDAAGGTVSRGAVDARVDAVVWPMNGMLERPTGFETLGGLSSPGPLWTVVALVTGGAVLILGGAAYGPVAKRAEASRARRGTEAAGGR

Formula C1157H1872N342O353S8

Absent Amino Acids

Common Amino Acids G

Mass 26478.15

PI 9.56

Basic Residues 29

Acidic Residues 24

Hydrophobic Residues 107

Net Charge +4

Boman Index 43.44

Hydrophobicity 0.028

Aliphatic Index 83.88

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 28085

Absorbance 280nm 106.07

Polar Residues 48

number

31

A

21

R

4

N

14

D

2

C

10

E

4

Q

39

G

1

H

4

I

19

L

7

K

6

M

6

F

15

P

14

S

20

T

4

W

4

Y

33

V

Amino Acid Distribution

A: 31 R: 21 N: 4 D: 14 C: 2 E: 10 Q: 4 G: 39 H: 1 I: 4 L: 19 K: 7 M: 6 F: 6 P: 15 S: 14 T: 20 W: 4 Y: 4 V: 33

Length

258

Formula

C1157H1872N342O353S8

Mass

26478.15

PI

9.56

Net Charge

+4

Boman Index

43.44

Hydrophobicity

0.028

Evidence 1 Activity

Source & Reference

Database Source dbACP